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Crystal structure of serotonin
The title compound, serotonin or 5-hy-droxy-tryptamine (5-HT) [systematic name: 3-(2-amino-eth-yl)-1 -indol-5-ol], C H N O, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is - [C -C -C -C and C -C -C -N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (...
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| Published in: | Acta crystallographica. Section E, Crystallographic communications Crystallographic communications, 2022-04, Vol.78 (Pt 4), p.365-368 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c465t-647b5c650859a42b58d3d9f853082e95c8d4091d9e8bb8eeaa1280a94e86ad4c3 |
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| cites | cdi_FETCH-LOGICAL-c465t-647b5c650859a42b58d3d9f853082e95c8d4091d9e8bb8eeaa1280a94e86ad4c3 |
| container_end_page | 368 |
| container_issue | Pt 4 |
| container_start_page | 365 |
| container_title | Acta crystallographica. Section E, Crystallographic communications |
| container_volume | 78 |
| creator | Naeem, Marilyn Chadeayne, Andrew R Golen, James A Manke, David R |
| description | The title compound, serotonin or 5-hy-droxy-tryptamine (5-HT) [systematic name: 3-(2-amino-eth-yl)-1
-indol-5-ol], C
H
N
O, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is
-
[C
-C
-C
-C
and C
-C
-C
-N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (3) and -61.9 (2)°, respectively]. In the crystal, the mol-ecules are linked into a three-dimensional network by N-H⋯O and O-H⋯N hydrogen bonds. |
| doi_str_mv | 10.1107/S2056989022002559 |
| format | article |
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-indol-5-ol], C
H
N
O, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is
-
[C
-C
-C
-C
and C
-C
-C
-N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (3) and -61.9 (2)°, respectively]. In the crystal, the mol-ecules are linked into a three-dimensional network by N-H⋯O and O-H⋯N hydrogen bonds.</description><identifier>ISSN: 2056-9890</identifier><identifier>EISSN: 2056-9890</identifier><identifier>DOI: 10.1107/S2056989022002559</identifier><identifier>PMID: 35492269</identifier><language>eng</language><publisher>England: International Union of Crystallography</publisher><subject>crystal structure ; free base ; indole ; Research Communications ; serotonin ; tryptamine</subject><ispartof>Acta crystallographica. Section E, Crystallographic communications, 2022-04, Vol.78 (Pt 4), p.365-368</ispartof><rights>Naeem et al. 2022.</rights><rights>Naeem et al. 2022 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-647b5c650859a42b58d3d9f853082e95c8d4091d9e8bb8eeaa1280a94e86ad4c3</citedby><cites>FETCH-LOGICAL-c465t-647b5c650859a42b58d3d9f853082e95c8d4091d9e8bb8eeaa1280a94e86ad4c3</cites><orcidid>0000-0002-2513-4801</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983975/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983975/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35492269$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Naeem, Marilyn</creatorcontrib><creatorcontrib>Chadeayne, Andrew R</creatorcontrib><creatorcontrib>Golen, James A</creatorcontrib><creatorcontrib>Manke, David R</creatorcontrib><title>Crystal structure of serotonin</title><title>Acta crystallographica. Section E, Crystallographic communications</title><addtitle>Acta Crystallogr E Crystallogr Commun</addtitle><description>The title compound, serotonin or 5-hy-droxy-tryptamine (5-HT) [systematic name: 3-(2-amino-eth-yl)-1
-indol-5-ol], C
H
N
O, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is
-
[C
-C
-C
-C
and C
-C
-C
-N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (3) and -61.9 (2)°, respectively]. In the crystal, the mol-ecules are linked into a three-dimensional network by N-H⋯O and O-H⋯N hydrogen bonds.</description><subject>crystal structure</subject><subject>free base</subject><subject>indole</subject><subject>Research Communications</subject><subject>serotonin</subject><subject>tryptamine</subject><issn>2056-9890</issn><issn>2056-9890</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNplkU1LAzEQhoMoKrU_wIv06KU6-ZhschGk-FEQPKjnkE2murLdaLIr-O9trYriaYZ33nlm4GXskMMJ51Cd3glAbY0FIQAEot1i-2tputa2f_V7bFzKMwBwhVKj2GV7EpUVQtt9djTL76X37aT0eQj9kGmSFpNCOfWpa7oDtrPwbaHxVx2xh8uL-9n19Ob2aj47v5kGpbGfalXVGDSCQeuVqNFEGe3CoAQjyGIwUYHl0ZKpa0PkPRcGvFVktI8qyBGbb7gx-Wf3kpulz-8u-cZ9Cik_Op_7JrTkYhWt4EC-4qRqUxtVQYySY2UQuMAV62zDehnqJcVAXZ99-wf6d9I1T-4xvTljjbTVGnD8BcjpdaDSu2VTArWt7ygNxQmNRitVCbmy8o015FRKpsXPGQ5uHZP7F9Nq5-j3fz8b36HID_Jni4o</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Naeem, Marilyn</creator><creator>Chadeayne, Andrew R</creator><creator>Golen, James A</creator><creator>Manke, David R</creator><general>International Union of Crystallography</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-2513-4801</orcidid></search><sort><creationdate>20220401</creationdate><title>Crystal structure of serotonin</title><author>Naeem, Marilyn ; Chadeayne, Andrew R ; Golen, James A ; Manke, David R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-647b5c650859a42b58d3d9f853082e95c8d4091d9e8bb8eeaa1280a94e86ad4c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>crystal structure</topic><topic>free base</topic><topic>indole</topic><topic>Research Communications</topic><topic>serotonin</topic><topic>tryptamine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Naeem, Marilyn</creatorcontrib><creatorcontrib>Chadeayne, Andrew R</creatorcontrib><creatorcontrib>Golen, James A</creatorcontrib><creatorcontrib>Manke, David R</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Acta crystallographica. Section E, Crystallographic communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naeem, Marilyn</au><au>Chadeayne, Andrew R</au><au>Golen, James A</au><au>Manke, David R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Crystal structure of serotonin</atitle><jtitle>Acta crystallographica. Section E, Crystallographic communications</jtitle><addtitle>Acta Crystallogr E Crystallogr Commun</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>78</volume><issue>Pt 4</issue><spage>365</spage><epage>368</epage><pages>365-368</pages><issn>2056-9890</issn><eissn>2056-9890</eissn><abstract>The title compound, serotonin or 5-hy-droxy-tryptamine (5-HT) [systematic name: 3-(2-amino-eth-yl)-1
-indol-5-ol], C
H
N
O, has one mol-ecule in the asymmetric unit. The conformation of the ethyl-amino side chain is
-
[C
-C
-C
-C
and C
-C
-C
-N (a = aromatic, m = methyl-ene) torsion angles = -64.2 (3) and -61.9 (2)°, respectively]. In the crystal, the mol-ecules are linked into a three-dimensional network by N-H⋯O and O-H⋯N hydrogen bonds.</abstract><cop>England</cop><pub>International Union of Crystallography</pub><pmid>35492269</pmid><doi>10.1107/S2056989022002559</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0002-2513-4801</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2056-9890 |
| ispartof | Acta crystallographica. Section E, Crystallographic communications, 2022-04, Vol.78 (Pt 4), p.365-368 |
| issn | 2056-9890 2056-9890 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_d7d9210ea71e4b8b8470dd3157850125 |
| source | PubMed Central |
| subjects | crystal structure free base indole Research Communications serotonin tryptamine |
| title | Crystal structure of serotonin |
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