Role of Systemic Antibiotics in Preventing Epidermal Growth Factor Receptor: Tyrosine Kinase Inhibitors-induced Skin Toxicities

The epidermal growth factor receptor (EGFR) is actively involved in the growth of multiple tumor types and has been found as an effective treatment target in various solid cancers, for example, lung cancer and head and neck cancer. Of effective drugs which target and inhibit EGFR functions, tyrosine...

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Bibliographic Details
Published in:Asia-Pacific journal of oncology nursing 2017-10, Vol.4 (4), p.323-329
Main Authors: Dsouza, Philomena Charlotte, Kumar, Shiyam
Format: Article
Language:English
Subjects:
Epidermal growth factor receptor
papulopustular rash
Review
skin toxicity
tyrosine kinase inhibitors
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Summary:The epidermal growth factor receptor (EGFR) is actively involved in the growth of multiple tumor types and has been found as an effective treatment target in various solid cancers, for example, lung cancer and head and neck cancer. Of effective drugs which target and inhibit EGFR functions, tyrosine kinase inhibitors have shown promising results, albeit at a cost of side effects, skin toxicity being the most common. This article provides an evidence-based strategy to oncology nurse practitioners in dealing with such toxicity.
ISSN:2347-5625
2349-6673
DOI:10.4103/apjon.apjon_28_17