Diversity of Antimicrobial Resistance Phenotypes in Salmonella Isolated from Commercial Poultry Farms

remains the leading cause of foodborne illness in the United States, and the dissemination of drug-resistant through the food chain has important implications for treatment failure of salmonellosis. We investigated the ecology of in integrated broiler production in order to understand the flow of an...

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Bibliographic Details
Published in:Frontiers in veterinary science 2017-06, Vol.4, p.96-96
Main Authors: Liljebjelke, Karen A, Hofacre, Charles L, White, David G, Ayers, Sherry, Lee, Margie D, Maurer, John J
Format: Article
Language:English
Subjects:
antimicrobial resistance
poultry
Salmonella
strain type
vertical transmission
Veterinary Science
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Summary:remains the leading cause of foodborne illness in the United States, and the dissemination of drug-resistant through the food chain has important implications for treatment failure of salmonellosis. We investigated the ecology of in integrated broiler production in order to understand the flow of antibiotic susceptible and resistant strains within this system. Data were analyzed from a retrospective study focused on antimicrobial resistant recovered from commercial broiler chicken farms conducted during the initial years of the US FDA's foray into retail meat surveillance by the National Antimicrobial Resistance Monitoring System (NARMS). Sixty-three percentage of were pan-susceptible to a panel of 19 antimicrobials used by the NARMS program. Twenty-five antimicrobial resistance phenotypes were observed in isolated from two broiler chicken farms. However, displaying resistance to streptomycin, alone, and in combination with other antibiotics was the most prevalent (36.3%) antimicrobial resistance phenotype observed. Resistance to streptomycin and sulfadimethoxine appeared to be linked to the transposon, Tn . Combinations of resistance against streptomycin, gentamicin, sulfadimethoxine, trimethoprim, and tetracycline were observed for a variety of serovars and genetic types as defined by pulsed-field gel electrophoresis. There were within and between farm differences in the antibiotic susceptibilities of and some of these differences were linked to specific serovars. However, farm differences were not linked to antibiotic usage. Analysis of the temporal and spatial distribution of the endemic serovars on these farms suggests that preventing vertical transmission of antibiotic-resistant would reduce carcass contamination with antibiotic-resistant and subsequently human risk exposure.
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2017.00096