Oxidative Stress and Antioxidant Status in Patients with Bell’s Palsy

Bell’s palsy (BP) is the most common acute mononeuropathy of unilateral facial paralysis. Immune, infective and ischaemic mechanisms are potential contributors to the development of BP, but the precise cause remains unclear. Recently, oxidative stress has been proposed as a risk factor of various id...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical biochemistry 2017-01, Vol.36 (1), p.18-22
Main Authors: Terzi, Suat, Dursun, Engin, Yılmaz, Adnan, Coşkun, Zerrin Özergin, Özgür, Abdulkadir, Çeliker, Metin, Demirci, Münir
Format: Article
Language:English
Subjects:
Bell’s palsy
Original Paper
oxidative stress
total anti - oxidant status
total antioxidant status
total oxidant status
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Bell’s palsy (BP) is the most common acute mononeuropathy of unilateral facial paralysis. Immune, infective and ischaemic mechanisms are potential contributors to the development of BP, but the precise cause remains unclear. Recently, oxidative stress has been proposed as a risk factor of various idiopathic diseases. The aim of this study was to investigate the possible role of oxidative stress in patients with BP. Thirty-two patients with BP and 30 healthy controls were included in this study. Serum total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) were measured by the Erel method. Serum TOS activities and OSI values were significantly higher in patients with BP compared with the control group ( 0.05). The data suggest that oxidative stress is increased in BP. These results of high oxidative stress in patients with BP may be helpful to clarify the etiopathogenesis of BP and contribute to improvement in the management or prevention of the disease.
ISSN:1452-8258
1452-8266
1452-8266
DOI:10.1515/jomb-2016-0033