MR imaging of primary benign cardiac tumors in the pediatric population

• Published in: Heliyon 2023-09, Vol.9 (9), p.e19932-e19932, Article e19932
• Main Authors: Inserra, Maria Cristina, Cannizzaro, Maria Teresa, Passaniti, Giulia, Celona, Antonio, Secinaro, Aurelio, Curione, Davide, D'Angelo, Tommaso, Garretto, Orazio, Romeo, Placido
• Format: Article
• Language: English
• Subjects: Review
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2023.e19932

Primary cardiac tumors are rare in all ages, especially in children, with a reported prevalence range of 0.0017–0.28% in autopsy series. Due to their rarity, the diagnostic and therapeutic pathways reserved to them are usually described by single case reports, leading to the point where a common diagnostic protocol is imperative to obtain a differential diagnosis. The first diagnostic approach is done with transthoracic echocardiogram (TTE), due to its wide availability, low cost, absence of ionizing radiations and non-invasiveness. Several tumors are discovered incidentally and, in many cases, TTE is helpful to determine location, size and anatomical features, playing a key role in the differential diagnosis. In the last few years, cardiac magnetic resonance imaging (CMR) has had an increased role in the diagnostic pathway of pediatric cardiac masses, due to its high accuracy in characterizing mass tissue properties (especially for soft tissue), and in detecting tumor size, extent, pericardial/pleural effusion, leading to the correct diagnosis, treatment and follow-up. Therefore, nowadays, several consensus statements consider CMR as a leading imaging technique, thanks to its non-invasive tissue characterization, without the use of ionizing radiation, in an unrestricted field of view. As suggested by the most recent literature, the pediatric protocol is not so different from the adult one, adapted to the size and cardiac frequency of the patient, sometimes requiring special conditions such as free-breathing sequences and/or sedation or general anesthesia in non-cooperating patients.