Current diagnostic tools for coronaviruses–From laboratory diagnosis to POC diagnosis for COVID‐19

The Coronavirus‐2019 (COVID‐19) pandemic has put tremendous strain on healthcare systems worldwide. It is challenging for clinicians to differentiate COVID‐19 from other acute respiratory tract infections via clinical symptoms because those who are infected display a wide range of symptoms. An effec...

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Bibliographic Details
Published in:Bioengineering & Translational Medicine 2020-09, Vol.5 (3), p.e10177-n/a
Main Authors: Wang, Yung‐Chih, Lee, Yi‐Tzu, Yang, Ting, Sun, Jun‐Ren, Shen, Ching‐Fen, Cheng, Chao‐Min
Format: Article
Language:English
Subjects:
Antibodies
Coronaviruses
COVID‐19
Cytokines
Diagnostic software
Diagnostic systems
diagnostics
Health care
Middle East respiratory syndrome
point‐of‐care
Respiratory diseases
Review
Viral diseases
Viruses
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Summary:The Coronavirus‐2019 (COVID‐19) pandemic has put tremendous strain on healthcare systems worldwide. It is challenging for clinicians to differentiate COVID‐19 from other acute respiratory tract infections via clinical symptoms because those who are infected display a wide range of symptoms. An effective, point‐of‐care (POC) diagnostic tool could mitigate healthcare system strain, protect healthcare professionals, and support quarantine efforts. We believe that a POC tool can be developed that would be rapid, easy to use, and inexpensive. It could be used in the home, in resource‐limited areas, and even in clinical settings. In this article, we summarize the current state of COVID‐19 diagnostic methods and make a case for an all‐in‐one, highly sensitive POC assay that integrates antibody detection, protein detection, and serum cytokine detection to diagnose COVID‐19 infection. We believe this article will provide insights into the current state of diagnostics for COVID‐19, and promote additional research and tool development that could be exceptionally impactful.
ISSN:2380-6761
2380-6761
DOI:10.1002/btm2.10177