Comparative Analysis of Anal Colposcopy with Histology in the Follow-Up of Patients under Treatment for Anal Condyloma

Abstract Objectives  To compare morphological abnormalities on anal colposcopy against histology to determine anal high-grade squamous intraepithelial lesions (HSILs). Methods  This is a retrospective data assessment of HIV-negative and HIV-positive patients undergoing outpatient follow-up. The samp...

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Bibliographic Details
Published in:Journal of Coloproctology 2022-03, Vol.42 (1), p.063-067
Main Authors: Manzione, Thiago da Silveira, Nadal, Sidney Roberto, Gonçalves, Antônio José
Format: Article
Language:English
Subjects:
anal colposcopy
anal condyloma
anal high-grade squamous intraepithelial lesion
GASTROENTEROLOGY & HEPATOLOGY
high-resolution anoscopy
Original Article
SURGERY
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Summary:Abstract Objectives  To compare morphological abnormalities on anal colposcopy against histology to determine anal high-grade squamous intraepithelial lesions (HSILs). Methods  This is a retrospective data assessment of HIV-negative and HIV-positive patients undergoing outpatient follow-up. The sample comprised 54 patients presenting acetowhite lesions on anal colposcopy. Acetowhite lesions were classified according to their morphology into punctation, verrucous, mosaic, ulcerated, or hypervascularized, and biopsies of these specimens were classified as anal HSIL, low-grade squamous intraepithelial lesion (LSIL), or normal. The data were analyzed using SPSS for Windows version 13.0 (SPSS Inc., Chicago, IL, USA). The results were analyzed using the nonparametric Mann-Whitney test, the Fisher exact test and the chi-squared parametric test. A 95% confidence interval (CI) was used and a level of significance 
ISSN:2237-9363
2317-6423
2317-6423
DOI:10.1055/s-0041-1739299