Pagetoid dyskeratosis in dermatopathology

Currently, pagetoid dyskeratosis is believed to involve an accelerated keratinization process, possibly induced by mechanical trauma. It represents, in almost its totality, incidental histological findings of specific cells, except when it occurs in the hands, where it usually occurs simultaneously...

Full description

Saved in:
Bibliographic Details
Published in:Anais brasileiros de dermatología 2021-07, Vol.96 (4), p.454-457
Main Authors: Rocha, Tauana Ogata Coelho da, Moya, Fernanda Gonçalves, Vilella, Vívian Moreira, Lellis, Rute Facchini
Format: Article
Language:English
Subjects:
Clear epithelial cells
DERMATOLOGY
Dermatopathology
Dyskeratosis
Pagetoid dyskeratosis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Currently, pagetoid dyskeratosis is believed to involve an accelerated keratinization process, possibly induced by mechanical trauma. It represents, in almost its totality, incidental histological findings of specific cells, except when it occurs in the hands, where it usually occurs simultaneously with skin lesions and local dyschromia. These are large, rounded keratinocytes, with pale cytoplasm and a pyknotic nucleus surrounded by a clear halo, which can be easily mistaken by other skin diseases. Its etiology is not completely elucidated, and the correct identification of this entity can be of great importance in the differential diagnosis of skin disorders and the understanding of the keratinization process of the epidermis.
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1016/j.abd.2020.12.006