A practical treatment for COVID‐19 and the next pandemic

[...]investigators can only speculate on the origins of SARS-CoV-2 and its many variants: delta and more recently omicron. 3,4 Scientists and health officials believe we will eventually face another pandemic. [...]these drugs will be expensive for people living in developed countries and they will n...

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Published in:Pharmacology research & perspectives 2022-08, Vol.10 (4), p.e00988-n/a
Main Authors: Bhattacharya, Jahar, Booy, Robert, Casadevall, Arturo, Dela Cruz, Charles, Fedson, David S., Garcia, Joe G. N., Grohmann, Gary, Hung, Ivan F. N., Jacobson, Jeffrey R., Jennings, Lance C., Kobzik, Lester, Leligdowicz, Aleksandra, Liao, James K., Martin, Jennifer H., Musher, Daniel M., Serhan, Charles N., Tashiro, Masato
Format: Article
Language:English
Subjects:
ACE inhibitors
Angiotensin Receptor Antagonists
ARBs
COVID-19
COVID-19 vaccines
Generic drugs
Humans
Invited Review
Invited Reviews
Mortality
next pandemic
Pandemics
Pharmacology
SARS-CoV-2
Statins
treatment
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Summary:[...]investigators can only speculate on the origins of SARS-CoV-2 and its many variants: delta and more recently omicron. 3,4 Scientists and health officials believe we will eventually face another pandemic. [...]these drugs will be expensive for people living in developed countries and they will not be available in developing countries anytime soon. [...]antiviral resistance will always be a threat. Adapted from reference 15 First author Adjusted (ref) Methods HR/OR 95% CI p value Zhang 15 CCS, PSM (4:1) 0.58 0.43–0.80 .001 Rodriguez-Nava 15 cohort, ICU 0.38 0.18–0.77 .008 Mallow 15 Cohort 0.54 0.49–0.60
ISSN:2052-1707
2052-1707
DOI:10.1002/prp2.988