Two Cases of Refractory Large Granular Lymphocytic Leukemia Treated by Porcine Anti-human Thymocyte Immunoglobulin

To the Editor：Large granular lymphocytic leukemia （LGLL） is a rare chronic clonal lymphoproliferative disease characterized by a persistent increase in large granular lymphocytes,which are large lymphocytes with a low nucleus to cytoplasm ratio and an abundant cytoplasm with azurophilic granules....

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Bibliographic Details
Published in:Chinese medical journal 2015-03, Vol.128 (5), p.709-710
Main Authors: Zeng, Qiang, Wang, Hong, Chang, Hong
Format: Article
Language:English
Subjects:
Adult
Animals
Bone marrow
Case studies
Correspondence
Dosage and administration
Drug therapy
Female
Hematology
Humans
Immunoglobulins
Immunoglobulins - therapeutic use
Laboratories
Leukemia
Leukemia, Large Granular Lymphocytic - drug therapy
Lymphocytes
Lymphocytes - metabolism
Lymphocytic leukemia
Patients
Swine
T cell receptors
Thymocytes - immunology
免疫球蛋白
大颗粒
治疗
淋巴组织
淋巴细胞性白血病
猪用
细胞质
胸腺细胞
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Description
Summary:To the Editor：Large granular lymphocytic leukemia （LGLL） is a rare chronic clonal lymphoproliferative disease characterized by a persistent increase in large granular lymphocytes,which are large lymphocytes with a low nucleus to cytoplasm ratio and an abundant cytoplasm with azurophilic granules.
ISSN:0366-6999
2542-5641
DOI:10.4103/0366-6999.151706