Healthcare resource utilization and economic burden of multiple sclerosis in Chinese patients: results from a real-world survey

Multiple sclerosis (MS) is uncommon in China and the standard of care is underdeveloped, with limited utilization of disease-modifying treatment (DMT). An understanding of real-world disease burden (including direct medical, non-medical, and indirect costs, such as loss of productivity), is currentl...

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Bibliographic Details
Published in:Scientific reports 2024-07, Vol.14 (1), p.15183-10, Article 15183
Main Authors: Sun, Chenhan, Jia, Yusheng, Li, Hainan, Qiao, Xuanqi, Tang, Mi, Geng, Meiyan, Jones, Eddie, Pike, James, Unsworth, Mia, Hu, Min
Format: Article
Language:English
Subjects:
692/617/375/1411
692/700/3934
Adult
Autoimmune diseases
China
China - epidemiology
Cost of Illness
Cross-Sectional Studies
East Asian People
Economic burden
Female
Generalized linear models
Health care
Health Care Costs
Health Resources - economics
Health Resources - statistics & numerical data
Healthcare resource
Hospitalization - economics
Humanities and Social Sciences
Humans
Information processing
Male
Middle Aged
multidisciplinary
Multiple sclerosis
Multiple Sclerosis - economics
Multiple Sclerosis - therapy
Patient Acceptance of Health Care - statistics & numerical data
Patients
Productivity
Real world data
Resource utilization
Science
Science (multidisciplinary)
Severity of Illness Index
Statistical analysis
Survey
Surveys
Surveys and Questionnaires
Therapeutic applications
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Summary:Multiple sclerosis (MS) is uncommon in China and the standard of care is underdeveloped, with limited utilization of disease-modifying treatment (DMT). An understanding of real-world disease burden (including direct medical, non-medical, and indirect costs, such as loss of productivity), is currently lacking in this population. To investigate the overall burden of managing patients with MS in China, a cross-sectional survey of physicians and their consulting patients with MS was conducted in 2021. Physicians provided information on healthcare resource utilization (HCRU; consultations, hospitalizations, tests, medication) and associated costs. Patients provided data on changes in their life, productivity, and impairment of daily activities due to MS. Results were stratified by disease severity using generalized linear models, with a p value 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-64713-1