Factors associated with amputation among patients with diabetic foot ulcers in a Saudi population

• Published in: BMC research notes 2018-04, Vol.11 (1), p.260-260, Article 260
• Main Authors: Musa, Imad R, Ahmed, Mohanned O N, Sabir, Elsanousi Ibrahim, Alsheneber, Ibrahim F, Ibrahim, Elsayed M E, Mohamed, Gussay Badawi, Awadallah, Rasha Elamin, Abbas, Tarig, Gasim, Gasim Ibrahim
• Format: Article
• Language: English
• Subjects: Age; Aged; Amputation; Amputation, Surgical - statistics & numerical data; Armed forces; Blood tests; Complications; Diabetes; Diabetes mellitus; Diabetic Foot - blood; Diabetic Foot - epidemiology; Diabetic Foot - pathology; Diabetic Foot - surgery; Diabetic foot ulcers; Ethics; Female; Foot; Foot diseases; Hemoglobin; Humans; Infections; Ischemia; Leg ulcers; Male; Middle Aged; Patients; Population; Population studies; Prevalence studies (Epidemiology); Prospective Studies; Research Note; Risk factors; Saudi Arabia; Saudi Arabia - epidemiology; Ulcers
• ISSN: 1756-0500; 1756-0500
• DOI: 10.1186/s13104-018-3372-z

A prospective study was conducted at the Armed Forces Hospital, Dhahran, Saudi Arabia, between January 2015 and December 2016 to identify the risk factors associated with amputation among diabetic foot ulcers DFUs patients. In total, 82 patients were recruited. Fifty-five of the patients were males (67.07%), the mean (SD) age of the participants was 60 (± 11.4) years, the mean duration of diabetes was 8.5 (± 3.7) years, and the mean haemoglobin A1c was 4.8 (± 2.8)%. In Univariate analysis, older age and high white blood cell count (WBC) were factors associated with amputation (OR = 1.1, 95% CI = 1-1.1, P = 0.012; and OR = 383, 95% CI = 7.9-18,665, P = 0.003, respectively). On the other hand, an ischaemic ulcer was half as likely as a neuropathic ulcer to lead to amputation (OR = 0.5, 95% CI = 0.3-0.9, P = 0.036), and a higher Wagner's grade was found to be protective against amputation OR = 14.5, 95% CI = 4.3-49.4, P