Effects of Dietary Milled Seed Mixture on Fatty Acid Status and Inflammatory Markers in Patients on Hemodialysis

Background. Plant seeds have gained interest for their health benefits due to their fatty acid content. The objective of this study was to determine the effects of dietary consumption of milled sesame/pumpkin/flax seed mixture on glycemic control, serum lipids, phospholipid fatty acid status, and in...

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Published in:TheScientificWorld 2014-01, Vol.2014 (2014), p.1-9
Main Authors: Arsic, Aleksandra, Popovic, Tamara, Takic, Marija, Rasic-Milutinovic, Zorica, Perunicic-Pekovic, Gordana, Ristic-Medic, Danijela, Glibetic, Marija
Format: Article
Language:English
Subjects:
Adult
Biomarkers - blood
Blood Glucose
Clinical Study
Cross-Sectional Studies
Cucurbita - cytology
Dietary Supplements
Fatty acids
Fatty Acids - analysis
Fatty Acids - blood
Female
Flax - cytology
Follow-Up Studies
Food and nutrition
Health aspects
Hemodialysis
Hemodialysis patients
Humans
Insulin - blood
Interleukin-6 - blood
Lipids
Male
Middle Aged
Nutritional aspects
Polyunsaturated fatty acids
Pruritus - diet therapy
Pruritus - etiology
Renal Dialysis - adverse effects
Renal Insufficiency - diet therapy
Renal Insufficiency - therapy
Rodents
Seeds
Seeds - chemistry
Serbia
Sesamum - cytology
Studies
Triglycerides - blood
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Summary:Background. Plant seeds have gained interest for their health benefits due to their fatty acid content. The objective of this study was to determine the effects of dietary consumption of milled sesame/pumpkin/flax seed mixture on glycemic control, serum lipids, phospholipid fatty acid status, and inflammatory factors in patients on hemodialysis. Methods. Thirty patients with well nutrition status (18 male, 12 female) were enrolled in the study. Participants consumed 30 g of milled sesame/pumpkin/flax (6 g/6 g/18 g, resp.) seeds mixture added to their habitual diet. Results. Total n-6 and n-3 polyunsaturated fatty acids and levels of linoleic, dihomo-gamma-linolenic (DGLA), arachidonic, alpha-linolenic (ALA), eicosapentaenoic, docosapentaenoic, and docosahexaenoic (DHA) acid were increased after 12 weeks of supplementation. A significant decrease of the serum triglyceride level (P
ISSN:2356-6140
1537-744X
1537-744X
DOI:10.1155/2014/563576