A Review of the Potential Benefits of Plants Producing Berries in Skin Disorders

During the last 30 years, berries have gained great attention as functional food against several risk factors in chronic diseases. The number of related publications on Pubmed rose from 1000 items in 1990 to more than 11,000 in 2019. Despite the fact that a common and clear definition of “berries” i...

Full description

Saved in:
Bibliographic Details
Published in:Antioxidants 2020-06, Vol.9 (6), p.542
Main Authors: Piazza, Stefano, Fumagalli, Marco, Khalilpour, Saba, Martinelli, Giulia, Magnavacca, Andrea, Dell’Agli, Mario, Sangiovanni, Enrico
Format: Article
Language:English
Subjects:
Albinism
Anthocyanins
Anti-inflammatory agents
antioxidant
Antioxidants
Berries
berry
Cell adhesion & migration
Dermatitis
Edema
Fibroblasts
Flavonoids
Flavonols
Fruits
Gene expression
Health aspects
Immunomodulation
Inflammation
Ovaries
Oxidative stress
Prevention
Review
Risk factors
Skin
Skin diseases
Strawberries
Wound healing
wounds
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:During the last 30 years, berries have gained great attention as functional food against several risk factors in chronic diseases. The number of related publications on Pubmed rose from 1000 items in 1990 to more than 11,000 in 2019. Despite the fact that a common and clear definition of “berries” is not shared among different scientific areas, the phytochemical pattern of these fruits is mainly characterized by anthocyanins, flavanols, flavonols, and tannins, which showed antioxidant and anti-inflammatory properties in humans. Skin insults, like wounds, UV rays, and excessive inflammatory responses, may lead to chronic dermatological disorders, conditions often characterized by long-term treatments. The application of berries for skin protection is sustained by long traditional use, but many observations still require a clear pharmacological validation. This review summarizes the scientific evidence, published on EMBASE, MEDLINE, and Scholar, to identify extraction methods, way of administration, dose, and mechanism of action of berries for potential dermatological treatments. Promising in vitro and in vivo evidence of Punica granatum L. and Vitis vinifera L. supports wound healing and photoprotection, while Schisandra chinensis (Turcz.) Baill. and Vaccinium spp. showed clear immunomodulatory effects. Oral or topical administrations of these berries justify the evaluation of new translational studies to validate their efficacy in humans.
ISSN:2076-3921
2076-3921
DOI:10.3390/antiox9060542