The impact of surgery and age on mortality with primary trachea malignant tumors: a retrospective study based on propensity-score matching analysis

This study aimed to explore the survival significance of surgery and age on the prognosis of patients with primary trachea malignancies. The entire cohort of 637 patients with primary malignant trachea tumors was used to perform the main analyses. The data of those patients were from a public databa...

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Bibliographic Details
Published in:Journal of cardiothoracic surgery 2023-07, Vol.18 (1), p.224-224, Article 224
Main Authors: Ping, Chen, Liang, Jia, Liu, Zhi-Yuan, He, Jiang, Zhou, Ji-Yao, Cheng, Hao, Yuan, Guang-Da
Format: Article
Language:English
Subjects:
Age
Cancer
Chemotherapy
Classification
Comparative analysis
Connective tissue
Databases, Factual
Head & neck cancer
Health aspects
Humans
Lymphatic system
Malignancy
Marital Status
Matching
Medical prognosis
Medical research
Medicine, Experimental
Metastasis
Mortality
Neoplasms
Old patients
Patients
Primary trachea malignancy
Prognosis
Radiation therapy
Rank tests
Regression analysis
Retrospective Studies
Statistical analysis
Subgroup analysis
Surgery
Survival
Tomography
Trachea
Trachea - surgery
Tumors
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Summary:This study aimed to explore the survival significance of surgery and age on the prognosis of patients with primary trachea malignancies. The entire cohort of 637 patients with primary malignant trachea tumors was used to perform the main analyses. The data of those patients were from a public database. Overall survival (OS) curves were drawn by the Kaplan-Meier method and compared by the Log-rank test. The univariable and multivariable Cox regression analyses calculated the hazard ratio (HR) and 95% confidence interval (CI) for overall mortality. The propensity-score matching analysis was used to reduce the selection bias. Age, surgery, histological type, N classification, M classification, marital status, and tumor grading were identified as independent prognostic factors after eliminating confounding factors. The results of the Kaplan-Meier method revealed that patients with age 
ISSN:1749-8090
1749-8090
DOI:10.1186/s13019-023-02340-z