Recent advances in cancer detection using dynamic, stimuli-responsive supramolecular chemosensors. a focus review

In current chemistry, supramolecular materials that respond to a wide variety of external stimuli, such as solvents, temperature, light excitation, pH, and mechanical forces (pressure, stress, strain, and tension), have attracted considerable attention; for example, we have developed cyclodextrins,...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in chemistry 2024-10, Vol.12, p.1478034
Main Authors: Matsumoto, Kotaro, Nakagawa, Keiichi, Asanuma, Daisuke, Fukuhara, Gaku
Format: Article
Language:English
Subjects:
Chemistry
chemosensor
hydrostatic pressure
living cell
mechanobiology
supramolecular chemistry
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In current chemistry, supramolecular materials that respond to a wide variety of external stimuli, such as solvents, temperature, light excitation, pH, and mechanical forces (pressure, stress, strain, and tension), have attracted considerable attention; for example, we have developed cyclodextrins, cucurbiturils, pillararenes, calixarenes, crown ether-based chemical sensors, or chemosensors. These supramolecular chemosensors have potential applications in imaging, probing, and cancer detection. Recently, we focused on pressure, particularly solution-state hydrostatic pressure, from the viewpoint of cancer therapy. This Mini Review summarizes (i) why hydrostatic pressure is important, particularly in biology, and (ii) what we can do using hydrostatic pressure stimulation.
ISSN:2296-2646
2296-2646
DOI:10.3389/fchem.2024.1478034