Host genotype and environment affect the trade-off between horizontal and vertical transmission of the parasite Edhazardia aedis

If a parasite is able to transmit horizontally or vertically, which transmission mode will it choose? We investigated how the growth conditions and the genotype of the mosquito Aedes aegypti affect the transmission mode of the parasite Edhazardia aedis. In poor conditions the parasites were more lik...

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Bibliographic Details
Published in:BMC evolutionary biology 2018-04, Vol.18 (1), p.59-59, Article 59
Main Authors: Zilio, Giacomo, Thiévent, Kevin, Koella, Jacob C
Format: Article
Language:English
Subjects:
Aedes
Aedes - parasitology
Aedes albopictus
Analysis
Animals
Disease transmission
Environment
Genetic aspects
Genetic correlation
Genotype
Host-Parasite Interactions - genetics
Host-parasite relationships
Life Cycle Stages
Microsporidia - growth & development
Microsporidia - physiology
Microsporidiosis - parasitology
Microsporidiosis - transmission
Mixed-mode transmission
Parasite
Parasites - genetics
Parasites - growth & development
Reproduction
Trade-off
Virulence
Virulence (Microbiology)
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Summary:If a parasite is able to transmit horizontally or vertically, which transmission mode will it choose? We investigated how the growth conditions and the genotype of the mosquito Aedes aegypti affect the transmission mode of the parasite Edhazardia aedis. In poor conditions the parasites were more likely to be transmitted horizontally, whereas in favourable conditions they were more likely to be transmitted vertically. Unfavourable conditions delayed emergence, giving the parasite more time to produce its horizontally transmitted stage; in more favourable conditions mosquitoes have greater reproductive success, increasing the effectiveness of vertical transmission. In addition, the parasite's ability to transmit vertically was influenced by the genetic background of the host (i.e., its full-sib family), giving a genetic correlation between the host's life-history and which of the parasite's transmission mode it enables. In particular, genotypes with large bodies (and therefore high fecundity) were more likely to enable vertical transmission than genotypes with small bodies. This led to a trade-off among the host's families (which can be interpreted as a genetic correlation) for the parasite's transmission mode. Since horizontal transmission is linked to higher virulence than vertical transmission, the host's contribution to transmission mode has important consequences for the evolution of parasites with mixed-mode transmission.
ISSN:1471-2148
1471-2148
DOI:10.1186/s12862-018-1184-3