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Effects of almond, dried grape and dried cranberry consumption on endurance exercise performance, recovery and psychomotor speed: protocol of a randomised controlled trial

BackgroundFoods rich in nutrients, such as nitrate, nitrite, L-arginine and polyphenols, can promote the synthesis of nitric oxide (NO), which may induce ergogenic effects on endurance exercise performance. Thus, consuming foods rich in these components, such as almonds, dried grapes and dried cranb...

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Published in:BMJ Open Sport & Exercise Medicine 2019-08, Vol.5 (1), p.e000560-e000560
Main Authors: d'Unienville, Noah M A, Hill, Alison M, Coates, Alison M, Yandell, Catherine, Nelson, Maximillian J, Buckley, Jonathan D
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Buckley, Jonathan D
description BackgroundFoods rich in nutrients, such as nitrate, nitrite, L-arginine and polyphenols, can promote the synthesis of nitric oxide (NO), which may induce ergogenic effects on endurance exercise performance. Thus, consuming foods rich in these components, such as almonds, dried grapes and dried cranberries (AGC), may improve athletic performance. Additionally, the antioxidant properties of these foods may reduce oxidative damage induced by intense exercise, thus improving recovery and reducing fatigue from strenuous physical training. Improvements in NO synthesis may also promote cerebral blood flow, which may improve cognitive function.Methods and analysisNinety-six trained male cyclists or triathletes will be randomised to consume ~2550 kJ of either a mixture of AGC or a comparator snack food (oat bar) for 4 weeks during an overreaching endurance training protocol comprised of a 2-week heavy training phase, followed by a 2-week taper. The primary outcome is endurance exercise performance (5 min time-trial performance) and secondary outcomes include markers of NO synthesis (plasma and urinary nitrites and nitrates), muscle damage (serum creatine kinase and lactate dehydrogenase), oxidative stress (F2-isoprostanes), endurance exercise function (exercise efficiency, submaximal oxygen consumption and substrate utilisation), markers of internal training load (subjective well-being, rating of perceived exertion, maximal rate of heart rate increase and peak heart rate) and psychomotor speed (choice reaction time).ConclusionThis study will evaluate whether consuming AGC improves endurance exercise performance, recovery and psychomotor speed across an endurance training programme, and evaluate the mechanisms responsible for any improvement.Trial registration numberACTRN12618000360213.
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Thus, consuming foods rich in these components, such as almonds, dried grapes and dried cranberries (AGC), may improve athletic performance. Additionally, the antioxidant properties of these foods may reduce oxidative damage induced by intense exercise, thus improving recovery and reducing fatigue from strenuous physical training. Improvements in NO synthesis may also promote cerebral blood flow, which may improve cognitive function.Methods and analysisNinety-six trained male cyclists or triathletes will be randomised to consume ~2550 kJ of either a mixture of AGC or a comparator snack food (oat bar) for 4 weeks during an overreaching endurance training protocol comprised of a 2-week heavy training phase, followed by a 2-week taper. The primary outcome is endurance exercise performance (5 min time-trial performance) and secondary outcomes include markers of NO synthesis (plasma and urinary nitrites and nitrates), muscle damage (serum creatine kinase and lactate dehydrogenase), oxidative stress (F2-isoprostanes), endurance exercise function (exercise efficiency, submaximal oxygen consumption and substrate utilisation), markers of internal training load (subjective well-being, rating of perceived exertion, maximal rate of heart rate increase and peak heart rate) and psychomotor speed (choice reaction time).ConclusionThis study will evaluate whether consuming AGC improves endurance exercise performance, recovery and psychomotor speed across an endurance training programme, and evaluate the mechanisms responsible for any improvement.Trial registration numberACTRN12618000360213.</description><identifier>ISSN: 2055-7647</identifier><identifier>EISSN: 2055-7647</identifier><identifier>DOI: 10.1136/bmjsem-2019-000560</identifier><identifier>PMID: 31548903</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Antioxidants ; Berries ; Cognitive ability ; cognitive function ; Diet ; dried fruit ; Endurance ; Evidence-based medicine ; Exercise ; exercise performance ; Food ; Free radicals ; Heart rate ; Mass spectrometry ; Nitrates ; nitric oxide ; Oxidative stress ; Physiology ; Polyphenols ; Protocol ; recovery ; Recovery (Medical) ; Scientific imaging ; Social networks ; tree nuts ; Well being</subject><ispartof>BMJ Open Sport &amp; Exercise Medicine, 2019-08, Vol.5 (1), p.e000560-e000560</ispartof><rights>Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2019 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b573t-7f3da57c9c4efcf4b95101e1bcd59c24e54753aa0bd618de80f3c01bb8b3a21e3</citedby><cites>FETCH-LOGICAL-b573t-7f3da57c9c4efcf4b95101e1bcd59c24e54753aa0bd618de80f3c01bb8b3a21e3</cites><orcidid>0000-0002-4196-1321</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2288746110/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2288746110?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27549,27550,27924,27925,37012,37013,44590,53791,53793,55350,75126,77601,77632,77660,77686</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31548903$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>d'Unienville, Noah M A</creatorcontrib><creatorcontrib>Hill, Alison M</creatorcontrib><creatorcontrib>Coates, Alison M</creatorcontrib><creatorcontrib>Yandell, Catherine</creatorcontrib><creatorcontrib>Nelson, Maximillian J</creatorcontrib><creatorcontrib>Buckley, Jonathan D</creatorcontrib><title>Effects of almond, dried grape and dried cranberry consumption on endurance exercise performance, recovery and psychomotor speed: protocol of a randomised controlled trial</title><title>BMJ Open Sport &amp; Exercise Medicine</title><addtitle>BMJ Open Sp Ex Med</addtitle><addtitle>BMJ Open Sport Exerc Med</addtitle><addtitle>BMJ Open Sport Exerc Med</addtitle><description>BackgroundFoods rich in nutrients, such as nitrate, nitrite, L-arginine and polyphenols, can promote the synthesis of nitric oxide (NO), which may induce ergogenic effects on endurance exercise performance. Thus, consuming foods rich in these components, such as almonds, dried grapes and dried cranberries (AGC), may improve athletic performance. Additionally, the antioxidant properties of these foods may reduce oxidative damage induced by intense exercise, thus improving recovery and reducing fatigue from strenuous physical training. Improvements in NO synthesis may also promote cerebral blood flow, which may improve cognitive function.Methods and analysisNinety-six trained male cyclists or triathletes will be randomised to consume ~2550 kJ of either a mixture of AGC or a comparator snack food (oat bar) for 4 weeks during an overreaching endurance training protocol comprised of a 2-week heavy training phase, followed by a 2-week taper. The primary outcome is endurance exercise performance (5 min time-trial performance) and secondary outcomes include markers of NO synthesis (plasma and urinary nitrites and nitrates), muscle damage (serum creatine kinase and lactate dehydrogenase), oxidative stress (F2-isoprostanes), endurance exercise function (exercise efficiency, submaximal oxygen consumption and substrate utilisation), markers of internal training load (subjective well-being, rating of perceived exertion, maximal rate of heart rate increase and peak heart rate) and psychomotor speed (choice reaction time).ConclusionThis study will evaluate whether consuming AGC improves endurance exercise performance, recovery and psychomotor speed across an endurance training programme, and evaluate the mechanisms responsible for any improvement.Trial registration numberACTRN12618000360213.</description><subject>Antioxidants</subject><subject>Berries</subject><subject>Cognitive ability</subject><subject>cognitive function</subject><subject>Diet</subject><subject>dried fruit</subject><subject>Endurance</subject><subject>Evidence-based medicine</subject><subject>Exercise</subject><subject>exercise performance</subject><subject>Food</subject><subject>Free radicals</subject><subject>Heart rate</subject><subject>Mass spectrometry</subject><subject>Nitrates</subject><subject>nitric oxide</subject><subject>Oxidative stress</subject><subject>Physiology</subject><subject>Polyphenols</subject><subject>Protocol</subject><subject>recovery</subject><subject>Recovery (Medical)</subject><subject>Scientific imaging</subject><subject>Social networks</subject><subject>tree nuts</subject><subject>Well being</subject><issn>2055-7647</issn><issn>2055-7647</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNks1u1DAUhSMEolXbF2CBLLFh0bR2_JOEBRKqClSqxAbWln19M80oiYOdVMwz8ZI4zTC0LBCSJfva53y-tk6WvWL0gjGuLm2_jdjnBWV1TimVij7LjgsqZV4qUT5_tD7KzmLcJg1TSnBRvMyOOJOiqik_zn5eNw3CFIlviOl6P7hz4kKLjmyCGZGYwe1rCGawGMKOgB_i3I9T6weSBg5uTmeABH9ggDYiGTE0PvTL5jkJCP4ek29hjXEHd773kw8kjojuHRlDqsB3Dy2QRHK-TxC33DMF33VpOYXWdKfZi8Z0Ec_280n27eP116vP-e2XTzdXH25zK0s-5WXDnZEl1CCwgUbYWjLKkFlwsoZCoBSl5MZQ6xSrHFa04UCZtZXlpmDIT7Kbleu82eoxtL0JO-1Nqx82fNhoE6YWOtQOOAUQRhlmBAVaQZVY1BYOypJZmVjvV9Y42x4dYHqS6Z5An54M7Z3e-HutSs45Uwnwdg8I_vuMcdLpcwC7zgzo56iLolZKUUHrJH3zl3Tr5zCkr0qqqiqFYowmVbGqIPgYAzaHZhjVS7T0Gi29REuv0Uqm14-fcbD8DlIS5Ksgmf8PePFHf2jzH4ZffoLtQw</recordid><startdate>20190807</startdate><enddate>20190807</enddate><creator>d'Unienville, Noah M A</creator><creator>Hill, Alison M</creator><creator>Coates, Alison M</creator><creator>Yandell, Catherine</creator><creator>Nelson, Maximillian J</creator><creator>Buckley, Jonathan D</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-4196-1321</orcidid></search><sort><creationdate>20190807</creationdate><title>Effects of almond, dried grape and dried cranberry consumption on endurance exercise performance, recovery and psychomotor speed: protocol of a randomised controlled trial</title><author>d'Unienville, Noah M A ; 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Exercise Medicine</jtitle><stitle>BMJ Open Sp Ex Med</stitle><stitle>BMJ Open Sport Exerc Med</stitle><addtitle>BMJ Open Sport Exerc Med</addtitle><date>2019-08-07</date><risdate>2019</risdate><volume>5</volume><issue>1</issue><spage>e000560</spage><epage>e000560</epage><pages>e000560-e000560</pages><issn>2055-7647</issn><eissn>2055-7647</eissn><abstract>BackgroundFoods rich in nutrients, such as nitrate, nitrite, L-arginine and polyphenols, can promote the synthesis of nitric oxide (NO), which may induce ergogenic effects on endurance exercise performance. Thus, consuming foods rich in these components, such as almonds, dried grapes and dried cranberries (AGC), may improve athletic performance. Additionally, the antioxidant properties of these foods may reduce oxidative damage induced by intense exercise, thus improving recovery and reducing fatigue from strenuous physical training. Improvements in NO synthesis may also promote cerebral blood flow, which may improve cognitive function.Methods and analysisNinety-six trained male cyclists or triathletes will be randomised to consume ~2550 kJ of either a mixture of AGC or a comparator snack food (oat bar) for 4 weeks during an overreaching endurance training protocol comprised of a 2-week heavy training phase, followed by a 2-week taper. The primary outcome is endurance exercise performance (5 min time-trial performance) and secondary outcomes include markers of NO synthesis (plasma and urinary nitrites and nitrates), muscle damage (serum creatine kinase and lactate dehydrogenase), oxidative stress (F2-isoprostanes), endurance exercise function (exercise efficiency, submaximal oxygen consumption and substrate utilisation), markers of internal training load (subjective well-being, rating of perceived exertion, maximal rate of heart rate increase and peak heart rate) and psychomotor speed (choice reaction time).ConclusionThis study will evaluate whether consuming AGC improves endurance exercise performance, recovery and psychomotor speed across an endurance training programme, and evaluate the mechanisms responsible for any improvement.Trial registration numberACTRN12618000360213.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>31548903</pmid><doi>10.1136/bmjsem-2019-000560</doi><orcidid>https://orcid.org/0000-0002-4196-1321</orcidid><oa>free_for_read</oa></addata></record>
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subjects Antioxidants
Berries
Cognitive ability
cognitive function
Diet
dried fruit
Endurance
Evidence-based medicine
Exercise
exercise performance
Food
Free radicals
Heart rate
Mass spectrometry
Nitrates
nitric oxide
Oxidative stress
Physiology
Polyphenols
Protocol
recovery
Recovery (Medical)
Scientific imaging
Social networks
tree nuts
Well being
title Effects of almond, dried grape and dried cranberry consumption on endurance exercise performance, recovery and psychomotor speed: protocol of a randomised controlled trial
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