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The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients

In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnos...

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Bibliographic Details
Published in:Frontiers in cardiovascular medicine 2022-04, Vol.9, p.854750-854750
Main Authors: Borlotti, Alessandra, Thomaides-Brears, Helena, Georgiopoulos, Georgios, Banerjee, Rajarshi, Robson, Matthew D, Fusco, Dahlene N, Masci, Pier-Giorgio
Format: Article
Language:English
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Summary:In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.
ISSN:2297-055X
2297-055X
DOI:10.3389/fcvm.2022.854750