Safety and outcomes of short-term use of peripheral vasoactive infusions in critically ill paediatric population in the emergency department

Early restoration of oxygen delivery to end organs in paediatric patients experiencing shock states is critical to optimizing outcomes. However, obtaining central access in paediatric patients may be challenging in non-intensive care settings. There is limited literature on the use of peripheral vas...

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Bibliographic Details
Published in:Scientific reports 2022-09, Vol.12 (1), p.16340-7, Article 16340
Main Authors: Yeong, Y. Q., Chan, J. M. F., Chan, J. K. Y., Huang, H. L., Ong, G. Y.
Format: Article
Language:English
Subjects:
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Child
Critical Illness - therapy
Dopamine
Emergency medical care
Emergency Service, Hospital
Humanities and Social Sciences
Humans
multidisciplinary
Oxygen
Pediatrics
Retrospective Studies
Science
Science (multidisciplinary)
Septic shock
Vasoactive agents
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Summary:Early restoration of oxygen delivery to end organs in paediatric patients experiencing shock states is critical to optimizing outcomes. However, obtaining central access in paediatric patients may be challenging in non-intensive care settings. There is limited literature on the use of peripheral vasoactive infusions in the initial resuscitation of paediatric patients in the emergency department. The aims of this study were to report the associated complications of peripheral vasoactive infusions and describe our local experience on its use. This was a single-centre, retrospective study on all paediatric patients who received peripheral vasoactive infusions at our paediatric emergency department from 2009 to 2016. 65 patients were included in this study. No patients had any local or regional complications. The mean patient age was 8.29 years old (± 5.99). The most frequent diagnosis was septic shock (45, 69.2%). Dopamine was the most used peripheral vasoactive agent (71.2%). The median time to central agents was 2 h (IQR 1–4). 16(24.2%) received multiple peripheral infusions. We reported no complications of peripheral vasoactive infusions. Its use could serve as a bridge till central access is obtained. Considerations on the use of multiple peripheral vasoactive infusions in the emergency department setting needs further research.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-20510-2