C-Reactive protein and chest x-ray morphology in COVID-19 patients: Our single center experience

• Published in: Journal of Research in Applied and Basic Medical Sciences 2023-04, Vol.9 (2), p.103-108
• Main Author: Shah, Kunjan
• Format: Article
• Language: English
• Subjects: c-reactive protein (crp); chest x-ray morphology; covid-19; mortality
• ISSN: 2717-0098; 2717-0098
• DOI: 10.52547/rabms.9.2.103

Background & Aims:  Coronavirus disease-2019 (COVID-19) is a newly discovered viral illness for which there is no proven cure at this time. We sought to establish the value of C-reactive protein (CRP) levels and chest X-ray morphology in determining the severity of COVID-19 disease and to correlate them with related mortality. Materials & Methods:  Data of COVID-19 patients with clinical outcomes in a small-designated hospital in Nadiad (Gujarat, India), collected retrospectively from March 15 to May 31, 2020. Patients with COVID-19 had their admission CRP's prognostic value, and chest X-ray morphology assessed. Results:  Out of 85 patients enrolled, 72 survived and 13 died. With an area under the curve (AUC) of 0.808 (95 percent CI, 0.708–0.885; P=0.001), the ROC curve analysis revealed moderate accuracy to identified mortality. Our model had an elevated CRP value of 0.105 units, which corresponded to an increased mortality rate of 1.11 times (Wald=12.73, 1.11(1.05, 1.18). Conclusion:  In contrast to the RT-PCR test, our investigation found that CRP and chest X-ray morphology were excellent predictors of earlier diagnosed COVID-19 patients. We want to require a larger sample size and to identify an additional biomarker that reduces mortality.