Prevalence and trends of coronary artery disease risk factors and their effect on age of diagnosis in patients with established coronary artery disease: Tehran Heart Center (2005-2015)

• Published in: BMC cardiovascular disorders 2021-10, Vol.21 (1), p.477-477, Article 477
• Main Authors: Hosseini, Kaveh, Mortazavi, Seyedeh Hamideh, Sadeghian, Saeed, Ayati, Aryan, Nalini, Mahdi, Aminorroaya, Arya, Tavolinejad, Hamed, Salarifar, Mojtaba, Pourhosseini, Hamidreza, Aein, Afsaneh, Jalali, Arash, Bozorgi, Ali, Mehrani, Mehdi, Kamangar, Farin
• Format: Article
• Language: English
• Subjects: Age; Age Factors; Age factors in disease; Aged; Analysis; Angiography; Blood pressure; Body mass index; Cardiovascular disease; Cardiovascular risk factors; Cholesterol; Cigarettes; Comorbidity; Coronary Angiography; Coronary artery; Coronary artery disease; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - epidemiology; Coronary heart disease; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - epidemiology; Coronary vessels; Cross-Sectional Studies; Demographic aspects; Diabetes; Diabetes mellitus; Diagnosis; Disease prevention; Fasting; Female; Forecasts and trends; Heart; Heart Disease Risk Factors; Heart diseases; High density lipoprotein; Humans; Hypertension; Investigations; Iran - epidemiology; Laboratories; Life Style; Lipids; Male; Medical imaging; Middle Aged; Prevalence; Prevention; Public health; Registries; Regression analysis; Risk Assessment; Risk factors; Risk factors (Health); Serum lipids; Sex Factors; Smoking; Statistics; Stenosis; Time Factors; Trends; Triglycerides; Variables; Vein & artery diseases; Womens health
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-021-02293-y

Coronary artery disease (CAD) is a universal public health challenge, more prominently so in the low- and middle-income countries. In this study, we aimed to determine prevalence and trends of CAD risk factors in patients with documented CAD and to determine their effects on the age of CAD diagnosis. We conducted a registry-based, serial cross-sectional study using the coronary angiography data bank of the Tehran Heart Center. Adult patients who had obstructive (> 50% stenosis) CAD were included in the study. The prevalence and 11-year trends of conventional CAD risk factors were analyzed by sex and age, and their adjusted effects on the age of CAD diagnosis were calculated. From January 2005 to December 2015, data for 90,094 patients were included in this analysis. A total of 61,684 (68.5%) were men and 28,410 (31.5%) were women. Men were younger at diagnosis than women, with a mean age of 60.1 in men and 63.2 in women (p