A Rare Presentation of Clozapine-Induced DRESS Syndrome

Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) is an uncommon side effect of certain medications. It causes a skin reaction, with eosinophilia and other organ involvement. This case describes a presentation of a 32-year-old female with a past medical history significant for s...

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Published in:Case reports in medicine 2018-01, Vol.2018 (2018), p.1-3
Main Authors: Younger, Tina, Narang, Natasha, Rudha, Yasir, Moazez, Carmel
Format: Article
Language:English
Subjects:
Abdomen
Allergies
Antibiotics
Bipolar disorder
Blood
Case Report
Case reports
Case studies
Clozapine
Complications and side effects
Dermatology
Diagnosis
Dosage and administration
Drug therapy
Edema
Enzymes
Eosinophilia
Exanthema
Hepatitis
Hyperglycemia
Infections
Literature reviews
Liver
Lymphadenopathy
Mental disorders
Psychiatry
Psychopharmacology
Psychotropic drugs
Risk factors
Schizophrenia
Side effects
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Rudha, Yasir
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description Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) is an uncommon side effect of certain medications. It causes a skin reaction, with eosinophilia and other organ involvement. This case describes a presentation of a 32-year-old female with a past medical history significant for schizophrenia and bipolar disorder who presented for a rash. She had been started on clozapine 10 days prior to admission. After extensive workup she was found to have DRESS syndrome secondary to clozapine use. This is the second reported case in the literature of clozapine-induced DRESS syndrome. This case is unique because it is the first case to present with the common manifestations of DRESS syndrome including eosinophilia, rash, lymphadenopathy, and organ involvement after clozapine use.
doi_str_mv 10.1155/2018/1346351
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source Wiley-Blackwell Open Access Collection; Publicly Available Content Database; PubMed Central
subjects Abdomen
Allergies
Antibiotics
Bipolar disorder
Blood
Case Report
Case reports
Case studies
Clozapine
Complications and side effects
Dermatology
Diagnosis
Dosage and administration
Drug therapy
Edema
Enzymes
Eosinophilia
Exanthema
Hepatitis
Hyperglycemia
Infections
Literature reviews
Liver
Lymphadenopathy
Mental disorders
Psychiatry
Psychopharmacology
Psychotropic drugs
Risk factors
Schizophrenia
Side effects
title A Rare Presentation of Clozapine-Induced DRESS Syndrome
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