Case series of acute appendicitis association with SARS-CoV-2 infection

Describe the indications for surgical interventions in asymptomatic patients with SARS-CoV-2. We are unaware of previous reports of an association between SARS-CoV-2 and acute appendicitis. We performed a single institution retrospective review of SARS-CoV-2 pre-procedure testing and indications for...

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Bibliographic Details
Published in:BMC infectious diseases 2021-02, Vol.21 (1), p.217-4, Article 217
Main Authors: Prichard, Charlsea, Canning, Matthew, McWilliam-Ross, Kindra, Birbari, John, Parker, William, Wasson, Lori, Hollingsworth, John W
Format: Article
Language:English
Subjects:
Abdomen
Acute Disease
Adult
Appendicitis
Appendicitis - complications
Asymptomatic
Care and treatment
Chi-square test
Collaboration
Coronaviruses
COVID-19
COVID-19 - complications
COVID-19 - epidemiology
COVID19
Diagnosis
Disease
Female
Hospitals
Humans
Infections
Infectious diseases
Male
Middle Aged
Mortality
Pandemics
Pathogenesis
Pathology
Prevalence
Retrospective Studies
Risk factors
SARS-CoV-2
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Statistical tests
Surgery
Viral diseases
Viral infections
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Summary:Describe the indications for surgical interventions in asymptomatic patients with SARS-CoV-2. We are unaware of previous reports of an association between SARS-CoV-2 and acute appendicitis. We performed a single institution retrospective review of SARS-CoV-2 pre-procedure testing and indications for surgical intervention. Statistical comparisons were performed using Chi Square analysis or two-tailed Student T test. We report a high prevalence of SARS-CoV-2 in both all testing and pre-procedure testing during the enrollment period. We observe a high prevalence of acute appendicitis among patients identified to be SARS-CoV-2 positive during pre-procedure testing and without recognized symptoms of COVID19. We report a previously unrecognized association between SARS-CoV-2 and acute appendicitis.
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-021-05909-y