Change is in the air: key questions on the ‘Treatable Traits’ model for chronic airway diseases in primary care

Despite great advancements in the treatment of chronic airway diseases, improvements in morbidity and mortality have stalled in recent years. Asthma and chronic obstructive pulmonary disease are complex and heterogeneous diseases that require tailored management based on individual patient character...

Full description

Saved in:
Bibliographic Details
Published in:NPJ primary care respiratory medicine 2024-07, Vol.34 (1), p.21-7, Article 21
Main Authors: Agusti, Alvar, Gibson, Peter G., Heaney, Liam G., Thomas, Mike
Format: Article
Language:English
Subjects:
692/699/1785
692/700
Anxiety
Asthma
Asthma - therapy
Chronic obstructive pulmonary disease
Clinical medicine
Depression - therapy
Drug dosages
Humans
Inflammation
Internal Medicine
Medical personnel
Medicine
Medicine & Public Health
Morbidity
Mortality
Obesity - therapy
Patients
Perspective
Pneumology/Respiratory System
Primary care
Primary Care Medicine
Primary Health Care
Pulmonary Disease, Chronic Obstructive - physiopathology
Pulmonary Disease, Chronic Obstructive - therapy
Smoking - adverse effects
Smoking - epidemiology
Steroids
Thoracic Surgery
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Despite great advancements in the treatment of chronic airway diseases, improvements in morbidity and mortality have stalled in recent years. Asthma and chronic obstructive pulmonary disease are complex and heterogeneous diseases that require tailored management based on individual patient characteristics and needs. The Treatable Traits (TTs) approach aims to personalise and improve patient care through the identification and targeting of clinically relevant and modifiable pulmonary, extra-pulmonary and behavioural traits. In this article, we outline the rationale for TTs-based management and provide practical guidance for its application in primary care. To aid implementation, seven potential ‘prime’ traits are proposed: airflow obstruction, eosinophilic inflammation, adherence, inhaler technique, smoking, low body mass index/obesity and anxiety and depression—selected for their prevalence, recognisability and feasibility of use. Some of the key questions among healthcare professionals, that may be roadblocks to widespread application of a TTs model of care, are also addressed.
ISSN:2055-1010
2055-1010
DOI:10.1038/s41533-024-00381-y