Endothelial function in healthy centenarians living in the Madonie’s district (Italy)

Endothelial function declines with age and plays a critical role in cardiovascular health. Therefore, investigating endothelial function in successful aging models, such as centenarians, is of interest. Flow-mediated dilation (FMD) of the brachial artery is the gold standard for measuring endothelia...

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Bibliographic Details
Published in:Experimental gerontology 2024-07, Vol.192, p.112457-112457, Article 112457
Main Authors: Buscemi, Carola, Randazzo, Cristiana, Barile, Anna Maria, Caruso, Roberta, Colombrita, Piero, Lombardo, Martina, Verde, Piergiorgio Lo, Sottile, Natalia, Barbagallo, Mario, Buscemi, Silvio
Format: Article
Language:English
Subjects:
Aging
Atherosclerosis
Centenarians
Endothelial function
Flow-mediated dilation
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Summary:Endothelial function declines with age and plays a critical role in cardiovascular health. Therefore, investigating endothelial function in successful aging models, such as centenarians, is of interest. Flow-mediated dilation (FMD) of the brachial artery is the gold standard for measuring endothelial function in vivo in humans. Therefore, we investigated, for the first time, the FMD of the brachial artery in a group of healthy centenarians. Selected as part of the ABCD project (nutrition, cardiovascular wellness, and diabetes) centenarians (aged ≥100 years) living in the municipalities of Madonie (Palermo, Italy) were compared with a younger (aged
ISSN:0531-5565
1873-6815
DOI:10.1016/j.exger.2024.112457