Demographic and clinical characteristics and risk factors of stereoacuity in convergence insufficiency-type intermittent exotropia

• Published in: Heliyon 2024-07, Vol.10 (13), p.e33348, Article e33348
• Main Authors: Zhang, Lu, He, Kaiqiao, Wang, Zijian, Zhang, Guiou, Li, Namin, Yu, Xiaoni, Guo, Changmei
• Format: Article
• Language: English
• Subjects: Characteristics; Convergence insufficiency-type; Intermittent exotropia; Risk factors; Stereoacuity
• ISSN: 2405-8440; 2405-8440
• DOI: 10.1016/j.heliyon.2024.e33348

To investigate characteristics and risk factors of poor stereoacuity of Convergence insufficiency-type Intermittent Exotropia (CI-type X(T)). Observational, cross-sectional study. The medical records of 615 CI-type X(T) and 222 basic-type intermittent exotropia (X(T)) were enrolled from January 2018 to January 2022. The characteristics were compared between the two types, and the associations between clinical factors and poor stereoacuity were examined using logistic regression. Compared with basic-type X(T), earlier surgery age, shorter misalignment duration, and the smaller distance exodeviation were observed in CI-type X(T). The CI-type X(T) demonstrated better sensory status and lower incidence of ocular muscle dysfunction than did the basic-type X(T). The surgery age between 6 and 12 years (odds ratio [OR], 0.595; compared with ≤6 years) was inversely associated with poor near stereoacuity, whereas duration more than 4 years (OR, 2.474), amblyopia (OR, 4.057), large distance exodeviation (>60PD: OR, 2.462) and anisometropia (>2.00D: OR, 3.874) were positively associated with poor near stereoacuity. The onset age older than 6 years (6–9 years: OR, 0.397; >9 years: OR, 0.317) was associated with better distance stereoacuity, whereas large distance exodeviation (>60PD: OR, 23.513), and dominant eye best corrected visual acuity (BCVA) worsen than 0.20 (OR, 2.987) were positively associated with poor distance stereoacuity. CI-type X(T) declined surgery early, with small distance exodeviation, better sensory status, and low incidence of ocular muscle dysfunction. A strong dose-dependent link between early onset age, long misalignment duration, worse dominant eye BCVA, distance exodeviation, amblyopia, anisometropia, and poor stereoacuity was confirmed.