Safety and Efficacy of Tafenoquine for Plasmodium vivax Malaria Prophylaxis and Radical Cure: Overview and Perspectives

This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in malaria prophylaxis and radical cure are summarized and some of the latest TQ-related studies (published in 2020 and 2021) are highlig...

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Bibliographic Details
Published in:Therapeutics and clinical risk management 2021-01, Vol.17, p.989-999
Main Author: Markus, Miles B
Format: Article
Language:English
Subjects:
Asexuality
Biology
Bone marrow
chloroquine
Disease prevention
Drug therapy
Erythrocytes
Ethylenediaminetetraacetic acid
g6pd
hypnozoite
Infections
Liver
Malaria
Parasites
Plasmodium falciparum
Primaquine
relapse
Spleen
Tafenoquine
Terminology
wr238605
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Summary:This article is inter alia a brief, first-stop guide to possible adverse events (AEs) associated with tafenoquine (TQ) intake. Safety and efficacy findings for TQ in malaria prophylaxis and radical cure are summarized and some of the latest TQ-related studies (published in 2020 and 2021) are highlighted. In addition, little-known biological and other matters concerning malaria parasites and 8-aminoquinoline (8-AQ) drug action are discussed and some correct terminology pertinent to malaria is explained.
ISSN:1176-6336
1178-203X
1178-203X
DOI:10.2147/TCRM.S269336