Biomechanical changes of degenerated adjacent segment and intact lumbar spine after lumbosacral topping-off surgery: a three-dimensional finite element analysis

• Published in: BMC musculoskeletal disorders 2020-02, Vol.21 (1), p.104-104, Article 104
• Main Authors: Cao, Liangliang, Liu, Yumei, Mei, Wei, Xu, Jianguang, Zhan, Shi
• Format: Article
• Language: English
• Subjects: Adult; Analysis; Biomechanical Phenomena; Biomechanics; Bone Screws; Bone surgery; CAT scans; Degeneration; Finite element; Finite Element Analysis; Finite element method; Fusion; Healthy Volunteers; Humans; Intervertebral Disc - physiology; Intervertebral Disc Degeneration - surgery; Intervertebral discs; Ligaments; Lumbar Vertebrae - diagnostic imaging; Lumbar Vertebrae - surgery; Lumbosacral Region - surgery; Male; Mechanical properties; Nucleus pulposus; Optical scanners; Patient outcomes; Physiological aspects; Range of motion; Range of Motion, Articular; Rotation; Spinal fusion; Spinal Fusion - methods; Spine; Spine (lumbar); Stress, Mechanical; Surgery; Technology; Tomography, X-Ray Computed; Topping-off; Weight-Bearing; Zygapophyseal Joint - physiology
• ISSN: 1471-2474; 1471-2474
• DOI: 10.1186/s12891-020-3128-5

Previous studies have revealed positive effect of Topping-off technique on upper adjacent segment after fusion surgery, while for the cases with fusion surgery on L5-S1 segment, owning maximal range of motion, and preexisting degenerated upper adjacent disc, it is necessary to clarify the superiority of Topping-ff technique and the effect exerted on the lumbar spine. A young healthy male volunteer was selected for thin-slice CT scanning. Then the image information was imported into the computer to establish the whole lumbar spine model as the health model. The medium degeneration model of intervertebral disc was established by changing the material properties of L4-S1 disc on the basis of the health model, and the fusion model and Topping-off model were respectively established on the basis of the degenerated model. The variation trend of ROM of L2-L5 and the stress changes of L4-L5 intervertebral disc, nucleus pulposus and facet joints were calculated respectively. The L4-L5 ROM of fusion model increased significantly but the ROM of L2-L3 and L3-L4 segments did not change significantly. Compared with the degenerated model, L4-L5 activity of the Topping-off model decreased, and ROM of the L2-L3 and L3-L4 increased to some extent in the flexion and extension positions. The stress on the disc, nucleus pulposus and facet joint of the fusion model L4-L5 increased in four positions of flexion, extension, rotation and bending compared with the degenerated model, while the fiber stress on the Topping-off model decreased significantly in all four positions. Topping-off technology can decrease the stress and ROM of the adjacent upper degenerated segment, and increase the ROM of other upper segments, thereby protecting the degenerated upper adjacent segments and compensating the lumbar spine mobility.