Medullary Aplasia Revealing a Metastatic Prostatic Adenocarcinoma

In this case report, we are reporting the case of a 68-year-old male patient who was admitted in our hospital for unintended weight loss, asthenia, and anorexia. Physical examination showed clinical signs of anemia such as pallor of skin and mucous membranes; hemodynamic parameters were normal. Comp...

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Bibliographic Details
Published in:Case reports in urology 2021, Vol.2021, p.8898130-5
Main Authors: Ziani, Idriss, Ibrahimi, Ahmed, Bellouki, Omar, Zaoui, Youssef, Housseini, Yasmine Laraqui, Zouidia, Fouad, Sayegh, Hachem El, Benslimane, Lounis, Nouini, Yassine
Format: Article
Language:English
Subjects:
Androgens
Anemia
Biopsy
Blood
Bone marrow
Cancer therapies
Case Report
Case reports
Chemotherapy
Endocrine therapy
Hemoglobin
Medical prognosis
Metastasis
Mortality
Patients
Prostate cancer
Thrombocytopenia
Tumors
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Summary:In this case report, we are reporting the case of a 68-year-old male patient who was admitted in our hospital for unintended weight loss, asthenia, and anorexia. Physical examination showed clinical signs of anemia such as pallor of skin and mucous membranes; hemodynamic parameters were normal. Complete blood count (CBC) analysis showed a pancytopenia with anemia, thrombocytopenia, and leukopenia. BM biopsy was performed, showing a malignant infiltration of bone marrow by a metastatic prostate cancer confirmed by immunohistochemistry. Prostate biopsy confirmed the diagnosis of acinar adenocarcinoma with Gleason score 8 (4+4), ISUP grade group 4. Our patient underwent chemical castration using LH-RH analogs in association with second-line hormone therapy by abiraterone acetate. The evolution was good on both the oncological and hematological levels.
ISSN:2090-696X
2090-6978
DOI:10.1155/2021/8898130