The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages

The aim of the study is to investigate the changes of serum leptin and kisspeptin levels in children and adolescents with different pubertal stages and nutritional states. A total of 647 Chinese children and adolescents were recruited, and serum estradiol, testosterone, pituitary gonadotropins, lept...

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Bibliographic Details
Published in:International Journal of Endocrinology 2016, Vol.2016 (2016), p.22-32-103
Main Authors: Gong, Fengying, Wu, Qinyong, Wang, Lin jie, Zhang, Dian xi, Li, Naishi, Pan, Hui, Li, Su juan, Zhu, Hui juan, Yang, Hong bo
Format: Article
Language:English
Subjects:
Age
Body fat
Body mass index
Children & youth
Cholesterol
Endocrinology
Females
Genetic aspects
Girls
Hypothalamus
Laboratories
Leptin
Mutation
Obesity
Physiological aspects
Puberty
Teenagers
Weight control
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Summary:The aim of the study is to investigate the changes of serum leptin and kisspeptin levels in children and adolescents with different pubertal stages and nutritional states. A total of 647 Chinese children and adolescents were recruited, and serum estradiol, testosterone, pituitary gonadotropins, leptin, and kisspeptin levels were measured. The results showed that serum leptin levels of boys in T2 stage were the highest among the five stages, while they showed a gradual increase from T1 to T5 stage in girls and reached the highest in T5 stage (P
ISSN:1687-8337
1687-8345
DOI:10.1155/2016/6790794