Surface Proteoglycans as Mediators in Bacterial Pathogens Infections

Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colon...

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Bibliographic Details
Published in:Frontiers in microbiology 2016-02, Vol.7, p.220-220
Main Authors: García, Beatriz, Merayo-Lloves, Jesús, Martin, Carla, Alcalde, Ignacio, Quirós, Luis M, Vazquez, Fernando
Format: Article
Language:English
Subjects:
Bacteria
Glycosaminoglycans
host interaction
Infection
Microbiology
Proteoglycans
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Summary:Infectious diseases remain an important global health problem. The interaction of a wide range of pathogen bacteria with host cells from many different tissues is frequently mediated by proteoglycans. These compounds are ubiquitous complex molecules which are not only involved in adherence and colonization, but can also participate in other steps of pathogenesis. To overcome the problem of microbial resistance to antibiotics new therapeutic agents could be developed based on the characteristics of the interaction of pathogens with proteoglycans.
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2016.00220