Retinal nerve fiber layer thickness and radial peripapillary capillaries density in myopic adults with optical coherence tomography angiography

• Published in: BMC ophthalmology 2024-09, Vol.24 (1), p.407-8, Article 407
• Main Authors: Ma, Chunhui, Chen, Chunwen, Zhang, Yutong, Yao, Jingyan
• Format: Article
• Language: English
• Subjects: Adult; Angiography; Axial Length, Eye - diagnostic imaging; Axial Length, Eye - pathology; Blood vessels; Capillaries; Capillaries - diagnostic imaging; Capillaries - pathology; Cross-Sectional Studies; CT imaging; Diagnosis; Female; Fluorescein Angiography - methods; Humans; Male; Measurement; Medical examination; Medical imaging; Middle Aged; Myopia; Nerve Fibers - pathology; Optic disc; Optic Disk - blood supply; Optic Disk - diagnostic imaging; Optic Disk - pathology; Optic nerve; Optical coherence tomography angiography (OCTA); Optics; Radial peripapillary capillaries (RPC); Regression analysis; Retina; Retinal Ganglion Cells - pathology; Retinal nerve fiber layer (RNFL); Retinal Vessels - diagnostic imaging; Retinal Vessels - pathology; Specific gravity; Tomography; Tomography, Optical Coherence - methods; Young Adult
• ISSN: 1471-2415; 1471-2415
• DOI: 10.1186/s12886-024-03673-6

To evaluate retinal nerve fiber layer thickness (RNFLT) and radial peripapillary capillaries (RPC) density in adults with different degrees of myopia using optical coherence tomography angiography (OCTA) and explore their relationship with ocular factors, such as axial length (AL) and disc area. A total of 188 subjects were included in this cross-sectional study. The eyes were divided into four groups according to AL. OCTA was used for the assessment of RNFLT, RPC density, and other optic disc measurements, such as disc area. One-way analysis of variance was performed to compare differences between four groups, and P value