Nonobstructive Acute Renal Failure with a Large Solitary Fibroid

A 38-year-old African American woman presenting with acute abdominal pain and nonobstructive renal failure was found to have an enlarged fibroid uterus. A differential for sepsis was considered. Lab evaluation revealed an elevated creatinine and myoglobin level at 3.9 mg/dL and 2140 ng/mL, respectiv...

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Bibliographic Details
Published in:Case reports in obstetrics and gynecology 2016-01, Vol.2016 (2016), p.1-5
Main Authors: Boren, Todd, Yılmaz, Ali, Mohling, S., Bakker, Blakele, Mashak, Zineb, Elkattah, Rayan, DePasquale, S.
Format: Article
Language:English
Subjects:
Abdomen
Antibiotics
Blood
Case Report
Fibroids
Gynecology
Hydration
Hysterectomy
Inflammation
Medical imaging
Mortality
Musculoskeletal system
Obstetrics
Open access
Pain
Postoperative period
Tomography
Urine
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Summary:A 38-year-old African American woman presenting with acute abdominal pain and nonobstructive renal failure was found to have an enlarged fibroid uterus. A differential for sepsis was considered. Lab evaluation revealed an elevated creatinine and myoglobin level at 3.9 mg/dL and 2140 ng/mL, respectively. Ongoing hemodynamic instability mandated surgery for acute abdomen. A 25 cm fibroid uterus was extirpated through a total abdominal hysterectomy. Immediate improvement of acute nephropathy mirrored the postoperative decline in serum myoglobin levels. Myoglobinemia from a massive degenerating fibroid is associated with nonobstructive acute renal failure.
ISSN:2090-6684
2090-6692
DOI:10.1155/2016/4039890