Reference values of myocardial native T1 and extracellular volume in patients without structural heart disease and had negative 3T cardiac magnetic resonance adenosine stress test

• Published in: International journal of cardiology. Heart & vasculature 2023-04, Vol.45, p.101181-101181, Article 101181
• Main Authors: Kositanurit, Weerapat, Theerasuwipakorn, Nonthikorn, Vorasettakarnkij, Yongkasem, Ponkanist, Kanokvalee, Lerdkhonsan, Chonthicha, Tumkosit, Monravee, Wendell, David C., Chattranukulchai, Pairoj
• Format: Article
• Language: English
• Subjects: 3 Tesla; Cardiac magnetic resonance; Extracellular volume; Native T1 mapping; Original Paper
• ISSN: 2352-9067; 2352-9067
• DOI: 10.1016/j.ijcha.2023.101181

To establish the reference values of native T1 and extracellular volume (ECV) in patients without structural heart disease and had a negative adenosine stress 3T cardiac magnetic resonance. Short-axis T1 mapping images were acquired using a modified Look-Locker inversion recovery technique before and after administration of 0.15 mmol/kg gadobutrol to calculate both native T1 and ECV. To compare the agreement between measurement strategies, regions of interest (ROI) were drawn in all 16 segments then averaged to represent mean global native T1. Additionally, an ROI was drawn in the mid-ventricular septum on the same image to represent the mid-ventricular septal native T1. Fifty-one patients (mean 65 years, 65 % women) were included. Mean global native T1 averaged from all 16 segments and a mid-ventricular septal native T1 were not significantly different (1221.2 ± 35.2 vs 1228.4 ± 43.7 ms, p = 0.21). Men had lower mean global native T1 (1195 ± 29.8 vs 1235.5 ± 29.4 ms, p