Primary Thrombotic Microangiopathy in Pediatric Patients

. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing , atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. . A retrospective study that included patients younger than 18 years diagnosed with primary thrombotic microangiopath...

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Bibliographic Details
Published in:Global pediatric health 2024, Vol.11, p.2333794X241307535
Main Authors: Aranzazu Ceballos, Andrés David, María Martínez Sánchez, Lina, Pamplona Sierra, Ana Paulina, Vergara Yánez, Daniela, Franco Hincapié, Liliana, Baquero Rodriguez, Richard
Format: Article
Language:English
Subjects:
E coli
Original
Toxins
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Summary:. Primary thrombotic microangiopathy includes hemolytic uremic syndrome caused by Shiga toxin-producing , atypical hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura. . A retrospective study that included patients younger than 18 years diagnosed with primary thrombotic microangiopathy between 2011 and 2021. . Thirty patients were included, of which 63% corresponded to a hemolytic uremic syndrome caused by Shiga toxin-producing , and 30% to the atypical hemolytic uremic syndrome. The median age was 2.8 years and female sex predominated at 57%. On admission to the emergency room, fever and fatigue were the most frequent symptoms (93%), followed by oliguria and anuria (80%). 48% of patients received hemodialysis during their care. Mortality was estimated at 13%. . This study constitutes the largest series of primary thrombotic microangiopathy in the pediatric population of Latin America, where the etiological and clinical behavior of this condition is described.
ISSN:2333-794X
2333-794X
DOI:10.1177/2333794X241307535