The correction of conjunctivochalasis using high-frequency radiowave electrosurgery improves dry eye disease

We aimed to determine the clinical impact of conjunctivochalasis (CCh) and its correction using high-frequency radiowave electrosurgery (HFR-ES), for signs and symptoms of dry eye disease (DED). Forty patients diagnosed with symptomatic CCh were prospectively enrolled. As a result, patients with CCh...

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Published in:Scientific reports 2021-01, Vol.11 (1), p.2551-2551, Article 2551
Main Authors: Ji, Yong Woo, Seong, Hyojin, Lee, Sujung, Alotaibi, Mutlaq Hamad, Kim, Tae-im, Lee, Hyung Keun, Seo, Kyoung Yul
Format: Article
Language:English
Subjects:
692/1807/1482
692/308/409
692/699/3161/3162
692/699/3161/3163
Eye
Eye diseases
Fluorescein
Humanities and Social Sciences
multidisciplinary
Reservoir capacity
Science
Science (multidisciplinary)
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Summary:We aimed to determine the clinical impact of conjunctivochalasis (CCh) and its correction using high-frequency radiowave electrosurgery (HFR-ES), for signs and symptoms of dry eye disease (DED). Forty patients diagnosed with symptomatic CCh were prospectively enrolled. As a result, patients with CCh had moderate to severe DED and most of them exhibited meibomian gland dysfunction (MGD). Corneo-conjunctival fluorescein staining score (CFS) and all lid-parallel-conjunctival-folds scores (LIPCOFs) were positively correlated. Nasal LIPCOF significantly correlated with symptoms and tear volume. Central, temporal, and total LIPCOF significantly correlated with MG loss, MGD stage, and lipid layer thickness. Independent significant factors associated with total LIPCOF included CFS, tear break-up time, and MGD stage. One month following HFR-ES, CCh was completely resolved in all cases. Patient age and preoperative nasal LIPCOF were determinants of outcomes associated with postoperative improvements in symptoms. Ocular surface parameters significantly improved, but MGD-related signs did not. Collectively, CCh associated with MGD severity deteriorates not only tear film stability and reservoir capacity, leading to DED exacerbation. Therefore, CCh should be corrected in patients with DED and MGD. Younger patients with nasal CCh are likely to experience more symptomatic relief after HFR-ES. Particularly, management for MGD should be maintained after CCh correction.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-82088-5