Loading…
Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children
Highlights • The purpose of this study was to explore the clinical and laboratory characterisitcs of children with refractory Mycoplasma pneumoniae pneumonia. • The clinical relevance to refractory Mycoplasma pneumoniae pneumonia is still largely debated all over world. Excessive inflammation maybe...
Saved in:
| Published in: | International journal of infectious diseases 2014-12, Vol.29 (C), p.18-23 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33 |
| container_end_page | 23 |
| container_issue | C |
| container_start_page | 18 |
| container_title | International journal of infectious diseases |
| container_volume | 29 |
| creator | Wang, Meijuan Wang, Yuqing Yan, Yongdong Zhu, Canhong Huang, Li Shao, Xuejun Xu, Jun Zhu, Hong Sun, Xiangle Ji, Wei Chen, Zhengrong |
| description | Highlights • The purpose of this study was to explore the clinical and laboratory characterisitcs of children with refractory Mycoplasma pneumoniae pneumonia. • The clinical relevance to refractory Mycoplasma pneumoniae pneumonia is still largely debated all over world. Excessive inflammation maybe play more important role in RMPP than macrolide resistance in China because of high prevalence of macrolide-resistant M. pneumonia. • In present study, Mycoplasma pneumoniae load is closely correlated with neutrophils and disease severity. Inflammatory indicators such as TNF-α and INF-γ also contribute to the progression of refractory Mycoplasma pneumoniae pneumonia. • In conclusion, both Mycoplasma pneumoniae load and excessive inflammation play a role in refractory Mycoplasma pneumoniae pneumonia. |
| doi_str_mv | 10.1016/j.ijid.2014.07.020 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_e0cca3d46e2748feb06868ad7df61ff8</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1201971214016051</els_id><doaj_id>oai_doaj_org_article_e0cca3d46e2748feb06868ad7df61ff8</doaj_id><sourcerecordid>1639498339</sourcerecordid><originalsourceid>FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33</originalsourceid><addsrcrecordid>eNpFkcuO1DAQRSMEYh7wAyxQlmwS_Ipjb5BQa4CRBrEANmysil0GhyRu7A5S_z3OdM-wcql865bqnqp6RUlLCZVvxzaMwbWMUNGSviWMPKkuqepVwztKn5a6fDW6p-yiusp5JIQIKdXz6oJ1QmjGyWX1YzeFJViYalhcPcEQExxiOtb7FH2YMNfR1wl9Anvf_ny0cT9BnqHeL7jOcQmA_8s6LLX9FSaXcHlRPfMwZXx5fq-r7x9uvu0-NXdfPt7u3t81tuPi0EgYiKNWq6EHJgQIRjotmdJOUd4h6QAlaO-kUtYytNDrjmInFeullp7z6-r25OsijGafwgzpaCIEc9-I6aeBdAh2QoPEWuBOSGS9UB4HIpVU4HrnJfVeFa83J69y_p8V88HMIVucJlgwrtlQybXQinNdpOwktSnmXCJ6XE2J2fiY0Wx8zMbHkN4UPmXo9dl_HWZ0jyMPQIrg3UmAJbG_AZOxZ0C_8Yh5jGtaSpiGmswMMV83xBthKspG0lH-Dyvnok8</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1639498339</pqid></control><display><type>article</type><title>Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children</title><source>BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS</source><source>ScienceDirect Journals</source><creator>Wang, Meijuan ; Wang, Yuqing ; Yan, Yongdong ; Zhu, Canhong ; Huang, Li ; Shao, Xuejun ; Xu, Jun ; Zhu, Hong ; Sun, Xiangle ; Ji, Wei ; Chen, Zhengrong</creator><creatorcontrib>Wang, Meijuan ; Wang, Yuqing ; Yan, Yongdong ; Zhu, Canhong ; Huang, Li ; Shao, Xuejun ; Xu, Jun ; Zhu, Hong ; Sun, Xiangle ; Ji, Wei ; Chen, Zhengrong</creatorcontrib><description>Highlights • The purpose of this study was to explore the clinical and laboratory characterisitcs of children with refractory Mycoplasma pneumoniae pneumonia. • The clinical relevance to refractory Mycoplasma pneumoniae pneumonia is still largely debated all over world. Excessive inflammation maybe play more important role in RMPP than macrolide resistance in China because of high prevalence of macrolide-resistant M. pneumonia. • In present study, Mycoplasma pneumoniae load is closely correlated with neutrophils and disease severity. Inflammatory indicators such as TNF-α and INF-γ also contribute to the progression of refractory Mycoplasma pneumoniae pneumonia. • In conclusion, both Mycoplasma pneumoniae load and excessive inflammation play a role in refractory Mycoplasma pneumoniae pneumonia.</description><identifier>ISSN: 1201-9712</identifier><identifier>EISSN: 1878-3511</identifier><identifier>DOI: 10.1016/j.ijid.2014.07.020</identifier><identifier>PMID: 25449230</identifier><language>eng</language><publisher>Canada: Elsevier</publisher><subject>Bronchoalveolar Lavage Fluid ; Child ; Child, Preschool ; Children ; Clinical characteristics ; DNA, Bacterial - analysis ; Female ; Fever - diagnosis ; Humans ; Infant ; Infectious Disease ; Interferon-gamma - blood ; Length of Stay ; Lung - pathology ; Male ; Mycoplasma pneumoniae - genetics ; Mycoplasma pneumoniae - isolation & purification ; Pneumonia, Mycoplasma - diagnosis ; Pneumonia, Mycoplasma - immunology ; Pulmonary/Respiratory ; Refractory Mycoplasma pneumoniae pneumonia ; Retrospective Studies ; Tumor Necrosis Factor-alpha - blood</subject><ispartof>International journal of infectious diseases, 2014-12, Vol.29 (C), p.18-23</ispartof><rights>The Authors</rights><rights>Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33</citedby><cites>FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25449230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Meijuan</creatorcontrib><creatorcontrib>Wang, Yuqing</creatorcontrib><creatorcontrib>Yan, Yongdong</creatorcontrib><creatorcontrib>Zhu, Canhong</creatorcontrib><creatorcontrib>Huang, Li</creatorcontrib><creatorcontrib>Shao, Xuejun</creatorcontrib><creatorcontrib>Xu, Jun</creatorcontrib><creatorcontrib>Zhu, Hong</creatorcontrib><creatorcontrib>Sun, Xiangle</creatorcontrib><creatorcontrib>Ji, Wei</creatorcontrib><creatorcontrib>Chen, Zhengrong</creatorcontrib><title>Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children</title><title>International journal of infectious diseases</title><addtitle>Int J Infect Dis</addtitle><description>Highlights • The purpose of this study was to explore the clinical and laboratory characterisitcs of children with refractory Mycoplasma pneumoniae pneumonia. • The clinical relevance to refractory Mycoplasma pneumoniae pneumonia is still largely debated all over world. Excessive inflammation maybe play more important role in RMPP than macrolide resistance in China because of high prevalence of macrolide-resistant M. pneumonia. • In present study, Mycoplasma pneumoniae load is closely correlated with neutrophils and disease severity. Inflammatory indicators such as TNF-α and INF-γ also contribute to the progression of refractory Mycoplasma pneumoniae pneumonia. • In conclusion, both Mycoplasma pneumoniae load and excessive inflammation play a role in refractory Mycoplasma pneumoniae pneumonia.</description><subject>Bronchoalveolar Lavage Fluid</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Clinical characteristics</subject><subject>DNA, Bacterial - analysis</subject><subject>Female</subject><subject>Fever - diagnosis</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious Disease</subject><subject>Interferon-gamma - blood</subject><subject>Length of Stay</subject><subject>Lung - pathology</subject><subject>Male</subject><subject>Mycoplasma pneumoniae - genetics</subject><subject>Mycoplasma pneumoniae - isolation & purification</subject><subject>Pneumonia, Mycoplasma - diagnosis</subject><subject>Pneumonia, Mycoplasma - immunology</subject><subject>Pulmonary/Respiratory</subject><subject>Refractory Mycoplasma pneumoniae pneumonia</subject><subject>Retrospective Studies</subject><subject>Tumor Necrosis Factor-alpha - blood</subject><issn>1201-9712</issn><issn>1878-3511</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpFkcuO1DAQRSMEYh7wAyxQlmwS_Ipjb5BQa4CRBrEANmysil0GhyRu7A5S_z3OdM-wcql865bqnqp6RUlLCZVvxzaMwbWMUNGSviWMPKkuqepVwztKn5a6fDW6p-yiusp5JIQIKdXz6oJ1QmjGyWX1YzeFJViYalhcPcEQExxiOtb7FH2YMNfR1wl9Anvf_ny0cT9BnqHeL7jOcQmA_8s6LLX9FSaXcHlRPfMwZXx5fq-r7x9uvu0-NXdfPt7u3t81tuPi0EgYiKNWq6EHJgQIRjotmdJOUd4h6QAlaO-kUtYytNDrjmInFeullp7z6-r25OsijGafwgzpaCIEc9-I6aeBdAh2QoPEWuBOSGS9UB4HIpVU4HrnJfVeFa83J69y_p8V88HMIVucJlgwrtlQybXQinNdpOwktSnmXCJ6XE2J2fiY0Wx8zMbHkN4UPmXo9dl_HWZ0jyMPQIrg3UmAJbG_AZOxZ0C_8Yh5jGtaSpiGmswMMV83xBthKspG0lH-Dyvnok8</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Wang, Meijuan</creator><creator>Wang, Yuqing</creator><creator>Yan, Yongdong</creator><creator>Zhu, Canhong</creator><creator>Huang, Li</creator><creator>Shao, Xuejun</creator><creator>Xu, Jun</creator><creator>Zhu, Hong</creator><creator>Sun, Xiangle</creator><creator>Ji, Wei</creator><creator>Chen, Zhengrong</creator><general>Elsevier</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>DOA</scope></search><sort><creationdate>20141201</creationdate><title>Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children</title><author>Wang, Meijuan ; Wang, Yuqing ; Yan, Yongdong ; Zhu, Canhong ; Huang, Li ; Shao, Xuejun ; Xu, Jun ; Zhu, Hong ; Sun, Xiangle ; Ji, Wei ; Chen, Zhengrong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Bronchoalveolar Lavage Fluid</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Clinical characteristics</topic><topic>DNA, Bacterial - analysis</topic><topic>Female</topic><topic>Fever - diagnosis</topic><topic>Humans</topic><topic>Infant</topic><topic>Infectious Disease</topic><topic>Interferon-gamma - blood</topic><topic>Length of Stay</topic><topic>Lung - pathology</topic><topic>Male</topic><topic>Mycoplasma pneumoniae - genetics</topic><topic>Mycoplasma pneumoniae - isolation & purification</topic><topic>Pneumonia, Mycoplasma - diagnosis</topic><topic>Pneumonia, Mycoplasma - immunology</topic><topic>Pulmonary/Respiratory</topic><topic>Refractory Mycoplasma pneumoniae pneumonia</topic><topic>Retrospective Studies</topic><topic>Tumor Necrosis Factor-alpha - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Meijuan</creatorcontrib><creatorcontrib>Wang, Yuqing</creatorcontrib><creatorcontrib>Yan, Yongdong</creatorcontrib><creatorcontrib>Zhu, Canhong</creatorcontrib><creatorcontrib>Huang, Li</creatorcontrib><creatorcontrib>Shao, Xuejun</creatorcontrib><creatorcontrib>Xu, Jun</creatorcontrib><creatorcontrib>Zhu, Hong</creatorcontrib><creatorcontrib>Sun, Xiangle</creatorcontrib><creatorcontrib>Ji, Wei</creatorcontrib><creatorcontrib>Chen, Zhengrong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>International journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Meijuan</au><au>Wang, Yuqing</au><au>Yan, Yongdong</au><au>Zhu, Canhong</au><au>Huang, Li</au><au>Shao, Xuejun</au><au>Xu, Jun</au><au>Zhu, Hong</au><au>Sun, Xiangle</au><au>Ji, Wei</au><au>Chen, Zhengrong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children</atitle><jtitle>International journal of infectious diseases</jtitle><addtitle>Int J Infect Dis</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>29</volume><issue>C</issue><spage>18</spage><epage>23</epage><pages>18-23</pages><issn>1201-9712</issn><eissn>1878-3511</eissn><abstract>Highlights • The purpose of this study was to explore the clinical and laboratory characterisitcs of children with refractory Mycoplasma pneumoniae pneumonia. • The clinical relevance to refractory Mycoplasma pneumoniae pneumonia is still largely debated all over world. Excessive inflammation maybe play more important role in RMPP than macrolide resistance in China because of high prevalence of macrolide-resistant M. pneumonia. • In present study, Mycoplasma pneumoniae load is closely correlated with neutrophils and disease severity. Inflammatory indicators such as TNF-α and INF-γ also contribute to the progression of refractory Mycoplasma pneumoniae pneumonia. • In conclusion, both Mycoplasma pneumoniae load and excessive inflammation play a role in refractory Mycoplasma pneumoniae pneumonia.</abstract><cop>Canada</cop><pub>Elsevier</pub><pmid>25449230</pmid><doi>10.1016/j.ijid.2014.07.020</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1201-9712 |
| ispartof | International journal of infectious diseases, 2014-12, Vol.29 (C), p.18-23 |
| issn | 1201-9712 1878-3511 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_e0cca3d46e2748feb06868ad7df61ff8 |
| source | BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS; ScienceDirect Journals |
| subjects | Bronchoalveolar Lavage Fluid Child Child, Preschool Children Clinical characteristics DNA, Bacterial - analysis Female Fever - diagnosis Humans Infant Infectious Disease Interferon-gamma - blood Length of Stay Lung - pathology Male Mycoplasma pneumoniae - genetics Mycoplasma pneumoniae - isolation & purification Pneumonia, Mycoplasma - diagnosis Pneumonia, Mycoplasma - immunology Pulmonary/Respiratory Refractory Mycoplasma pneumoniae pneumonia Retrospective Studies Tumor Necrosis Factor-alpha - blood |
| title | Clinical and laboratory profiles of refractory Mycoplasma pneumoniae pneumonia in children |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T07%3A47%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20and%20laboratory%20profiles%20of%20refractory%20Mycoplasma%20pneumoniae%20pneumonia%20in%20children&rft.jtitle=International%20journal%20of%20infectious%20diseases&rft.au=Wang,%20Meijuan&rft.date=2014-12-01&rft.volume=29&rft.issue=C&rft.spage=18&rft.epage=23&rft.pages=18-23&rft.issn=1201-9712&rft.eissn=1878-3511&rft_id=info:doi/10.1016/j.ijid.2014.07.020&rft_dat=%3Cproquest_doaj_%3E1639498339%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c534t-6ab0d1c98b7a244a420596289d8135e05ae6a9fd688cc2eca7951e56827696f33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1639498339&rft_id=info:pmid/25449230&rfr_iscdi=true |