Use of Parathyroid Hormone and Rehabilitation Reduces Subsequent Vertebral Body Fractures after Balloon Kyphoplasty

Retrospective cohort study. To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP). Although extensive studies have investigated the risk factors for SVBFs after BKP, few have rep...

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Published in:Asian spine journal 2022-06, Vol.16 (3), p.432-439
Main Authors: Ueno, Masaki, Toriumi, Emi, Yoshii, Aki, Tabata, Yuki, Furudate, Takeshi, Tajima, Yusuke
Format: Article
Language:English
Subjects:
Balloon treatment
balloon vertebroplasty
Bone density
Clinical Study
compression fracture
Fractures
Hospitalization
Intervention
Osteoporosis
Parathyroid hormone
Patients
Posture
Rehabilitation
Risk factors
Surgery
teriparatide
Vertebrae
Young adults
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Summary:Retrospective cohort study. To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP). Although extensive studies have investigated the risk factors for SVBFs after BKP, few have reported on postoperative therapies to prevent SVBFs and have evaluated their effectiveness. This study enrolled 273 patients who underwent an initial BKP. To treat osteoporosis, parathyroid hormone (PTH) administration was started 1-2 weeks before BKP and continued for at least 6 months postoperatively. Corsets were applied for 3 months after the procedure. Rehabilitative interventions, including hip range-of-motion training, muscle strengthening exercises, and motion/posture instruction, were started from the preoperative assessment time point and resumed 3 hours postoperatively. Corsets were used in all patients. Therefore, no grouping based on corset use was performed. PTH was used in 180 patients, and they were divided into the following two groups: PTH user group and PTH nonuser group. Rehabilitative interventions were provided to all patients for a median duration of 17 days. Patients who underwent rehabilitative intervention for
ISSN:1976-1902
1976-7846
DOI:10.31616/asj.2020.0608