One Health Surveillance of Antimicrobial Resistance Phenotypes in Selected Communities in Thailand

Integrated surveillance of antimicrobial resistance (AMR) using the approach that includes humans, animals, food, and the environment has been recommended by responsible international organizations. The objective of this study was to determine the prevalence of AMR phenotypes in and species isolated...

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Bibliographic Details
Published in:Antibiotics (Basel) 2022-04, Vol.11 (5), p.556
Main Authors: Sudatip, Duangdao, Tiengrim, Surapee, Chasiri, Kittipong, Kritiyakan, Anamika, Phanprasit, Wantanee, Morand, Serge, Thamlikitkul, Visanu
Format: Article
Language:English
Subjects:
Agriculture
Animals
Antibiotics
Antimicrobial agents
Antimicrobial resistance
antimicrobial resistance phenotype
Ceftriaxone
Chickens
Colistin
community
Drug resistance
E coli
Escherichia coli
Farmers
Farms
Food
Health surveillance
Hogs
International organizations
Klebsiella
Laboratories
Life Sciences
Medicine
Meropenem
One Health surveillance
Pathogens
Phenotypes
Poultry
Poultry farming
Rodents
Species
Surveillance
Thailand
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Summary:Integrated surveillance of antimicrobial resistance (AMR) using the approach that includes humans, animals, food, and the environment has been recommended by responsible international organizations. The objective of this study was to determine the prevalence of AMR phenotypes in and species isolated from humans, pigs, chickens, and wild rodents in five communities in northern Thailand. Rectal swabs from 269 pigs and 318 chickens; intestinal contents of 196 wild rodents; and stool samples from 69 pig farmers, 155 chicken farmers, and 61 non-farmers were cultured for and species, which were then tested for resistance to ceftriaxone, colistin, and meropenem. The prevalence of ceftriaxone-resistant and species in pigs, chickens, rodents, pig farmers, chicken farmers, and non-farmers was 64.3%, 12.9%, 4.1%, 55.1%, 38.7%, and 36.1%, respectively. Colistin resistance in pigs, chickens, rodents, pig farmers, chicken farmers, and non-farmers was 41.3%, 9.8%, 4.6%, 34.8%, 31.6%, and 24.6%, respectively. Meropenem resistance was not detected. The observed high prevalence of AMR, especially colistin resistance, in study food animals/humans is worrisome. Further studies to identify factors that contribute to AMR, strengthened reinforcement of existing regulations on antimicrobial use, and more appropriate interventions to minimize AMR in communities are urgently needed.
ISSN:2079-6382
2079-6382
DOI:10.3390/antibiotics11050556