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Characterization of Humicola pulvericola First Isolated from a Patient with Keratitis Clinical Case
Infection caused by the sp is extremely rare. We report the first case of fungal keratitis caused by ( ) in a 63-year-old man with a history of exposed to hot oil two weeks ago who developed keratitis. Direct examination of confocal microscopy and corneal scrapings showed fungal hyphae and isolates...
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Published in: | Infection and drug resistance 2024-06, Vol.17, p.2183-2188 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
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Summary: | Infection caused by the
sp is extremely rare. We report the first case of fungal keratitis caused by
(
) in a 63-year-old man with a history of exposed to hot oil two weeks ago who developed keratitis. Direct examination of confocal microscopy and corneal scrapings showed fungal hyphae and isolates were identified by morphology and by sequencing the internal transcribed spacer region of ribosomal DNA. The in vitro antifungal susceptibilities of the case strain were tested for five antifungal agents. The results showed that the infectious agent was resistant towards fluconazole, caspofungin and amphotericin B; itraconazole and voriconazole were highly effective against
. He was diagnosed with
keratitis and treated with oral itraconazole and natamycin eyedrops. After one month of treatment, the lesion gradually improved, with the best-corrected visual acuity improving to 0.8. |
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ISSN: | 1178-6973 1178-6973 |
DOI: | 10.2147/IDR.S468800 |