Epidemiology, risk factors, and prediction score of carbapenem resistance among inpatients colonized or infected with 3rd generation cephalosporin resistant Enterobacterales

In this study, we determined the incidence and risk factors of Carbapenem-resistant Enterobacterales (CRE) acquisition in inpatients with 3rd generation cephalosporin-resistant (3GCR) Enterobacterales at a tertiary-care hospital in Lebanon, and suggested a risk prediction score for it. This is a ret...

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Bibliographic Details
Published in:Scientific reports 2021-07, Vol.11 (1), p.14757-14757, Article 14757
Main Authors: Moghnieh, Rima, Abdallah, Dania, Jadayel, Marwa, Zorkot, Wael, El Masri, Hassan, Dib, Marie Joe, Omar, Tasnim, Sinno, Loubna, Lakkis, Rawad, Jisr, Tamima
Format: Article
Language:English
Subjects:
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Antibiotics
Cerebrovascular diseases
Endoscopy
Enterobacterales
Epidemiology
Ertapenem
Hospitals
Humanities and Social Sciences
Imipenem
Meropenem
multidisciplinary
Multivariate analysis
Nosocomial infection
Patients
Predictions
Regression analysis
Risk factors
Science
Science (multidisciplinary)
Statistics
Transplantation
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Summary:In this study, we determined the incidence and risk factors of Carbapenem-resistant Enterobacterales (CRE) acquisition in inpatients with 3rd generation cephalosporin-resistant (3GCR) Enterobacterales at a tertiary-care hospital in Lebanon, and suggested a risk prediction score for it. This is a retrospective matched case–control study of inpatients with 3GCR Enterobacterales that are carbapenem resistant (cases) versus those with carbapenem-sensitive isolates (controls). Data analysis was performed on IBM SPSS program, version 23.0 (Armonk, NY, USA: IBM Corp.). Categorical variables were compared between cases and controls through bivariate analysis and those with statistical significance ( P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-94295-1