Combined Evaluation of AFP, CA15-3, CA125, CA19-9, and CEA Tumor Markers in Patients with Hepatitis B and C

This study aimed to determine the role of tumor markers AFP, CA15-3, CA125, CA19-9 and CEA in patients with hepatitis B and C. This descriptive cross-sectional study was performed from Oct 2012 to Oct 2014. Serum samples of 129 patients with hepatitis B and C referred to Guilan Liver and Digestive D...

Full description

Saved in:
Bibliographic Details
Published in:Iranian journal of public health 2016-12, Vol.45 (12), p.1645-1651
Main Authors: Assmar, Mehdi, Yeganeh, Sara, Mansourghanaei, Fariborz, Amirmozafari, Nour
Format: Article
Language:English
Subjects:
Antigens
Biomarkers
Colorectal cancer
Consent
Disease prevention
Family medical history
Glycoproteins
Hepatitis
Immunoassay
Infections
Laboratories
Liver cancer
Liver diseases
Medical prognosis
NMR
Nuclear magnetic resonance
Original
Pancreatic cancer
Patients
Studies
Tumor markers, Hepatitis B, Hepatitis C, ELISA
Tumors
Urine
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study aimed to determine the role of tumor markers AFP, CA15-3, CA125, CA19-9 and CEA in patients with hepatitis B and C. This descriptive cross-sectional study was performed from Oct 2012 to Oct 2014. Serum samples of 129 patients with hepatitis B and C referred to Guilan Liver and Digestive Disease Research Center in Rasht, Iran were collected and checked for the existence of the listed tumor markers by ELISA. No increase in serum levels of tumor marker CA19-9, CEA and CA15-3 were seen in patients with hepatitis ( >0.05). In patients with hepatitis B, increase in CA125 were observed ( =0.03). In hepatitis C patients, there was an increase in AFP levels ( =0.03). The levels of AFP and CA125 markers were high in hepatitis C and hepatitis B, respectively. However, the increased levels were not seen is malignancy. Due to the small sample size, further study is necessary to find the reasons of the increase.
ISSN:2251-6085
2251-6093