Mitochondrial Metabolism Characterization of Four Different Fish Cell Lines

Mitochondria are a crucial cellular organelle that organizes a wide range of biological processes, from energy production and calcium homeostasis to cell proliferation, differentiation, and death as well as inflammation. Mitochondria also support immune cell phenotypes and function. The aim of this...

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Bibliographic Details
Published in:Fishes 2022-11, Vol.7 (6), p.354
Main Authors: Espinosa-Ruiz, Cristóbal, Mayor-Lafuente, Javier, Esteban, M. Ángeles
Format: Article
Language:English
Subjects:
Bioenergetics
Brain
Brain research
Calcium
Calcium homeostasis
cell culture
Cell death
Cell differentiation
Cell lines
Cell proliferation
Communication
Cytoplasmic organelles
energetic reserve
Fish
Hepatocellular carcinoma
Homeostasis
Marine fishes
Metabolism
Mitochondria
mitochondrial stress
Neoplasms
Phenotypes
Physiological aspects
Proliferation
Respiration
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Summary:Mitochondria are a crucial cellular organelle that organizes a wide range of biological processes, from energy production and calcium homeostasis to cell proliferation, differentiation, and death as well as inflammation. Mitochondria also support immune cell phenotypes and function. The aim of this communication is to evaluate the mitochondrial status and plasticity of four fish cell lines: SAF-1 (derived from gilthead sea bream skin), DLB-1 (derived from European sea bass brain), FuB-1 (established from mummichog brain), and PLHC-1 (a topminnow hepatocellular carcinoma). A mitochondrial stress assay was performed to compare the bioenergetic capabilities of these four fish cell lines as well as the importance of choosing the correct cell line when performing different in vitro studies.
ISSN:2410-3888
2410-3888
DOI:10.3390/fishes7060354