Pyrrolizidine alkaloids of senecio sp from Peru

Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species. The structures of these alkaloids were established by a complete NMR spectroscopic analysis, chemical transformations...

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Bibliographic Details
Published in:Química Nova 2011, Vol.34 (6), p.992-995
Main Authors: Artiles, Liliana Ruiz Vásquez and Matías Rei, Coloma, Azucena González, Pérez, Raimundo Cabrera, Mesia, Lastenia Ruiz
Format: Article
Language:English
Subjects:
19-acetoxysenkirkine
CHEMISTRY, MULTIDISCIPLINARY
pyrrolizidine alkaloids
Senecio
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Summary:Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species. The structures of these alkaloids were established by a complete NMR spectroscopic analysis, chemical transformations and comparison of their NMR data with those published for similar alkaloids. Three PAs were then tested for antifungal activity against Fusarium moniliforme, F. (Sheldon), F. oxysporum fs. lycopersici (Scheldt) and F. solani (Mart), no significant activity being observed.
ISSN:0100-4042
1678-7064
DOI:10.1590/S0100-40422011000600015