Species-specific climate Suitable Conditions Index and dengue transmission in Guangdong, China

• Published in: Parasites & vectors 2022-09, Vol.15 (1), p.1-342, Article 342
• Main Authors: Lu, Xinting, Bambrick, Hilary, Frentiu, Francesca D, Huang, Xiaodong, Davis, Callan, Li, Zhongjie, Yang, Weizhong, Devine, Gregor J, Hu, Wenbiao
• Format: Article
• Language: English
• Subjects: Aedes; Aedes aegypti; Aedes albopictus; Aquatic insects; Climate; Climate change; Climatic conditions; Confidence intervals; Dengue; Dengue fever; Dengue transmission; Disease; Disease transmission; Distribution; Entomology; Environmental aspects; Environmental factors; Epidemics; Fever; Geographical locations; Health aspects; Human diseases; Infections; Insects as carriers of disease; Interactive effect; Laboratories; Mosquitoes; Outbreaks; Pathogens; Pest outbreaks; Population; Precipitation; Probability theory; Regression models; Risk factors; Species; Statistical analysis; Suitable conditional index; Sympatry; Temperature; Vector-borne diseases; Vegetation; Viral diseases; Viruses; Weather
• ISSN: 1756-3305; 1756-3305
• DOI: 10.1186/s13071-022-05453-x

Optimal climatic conditions for dengue vector mosquito species may play a significant role in dengue transmission. We previously developed a species-specific Suitable Conditions Index (SCI) for Aedes aegypti and Aedes albopictus, respectively. These SCIs rank geographic locations based on their climatic suitability for each of these two dengue vector species and theoretically define parameters for transmission probability. The aim of the study presented here was to use these SCIs together with socio-environmental factors to predict dengue outbreaks in the real world. A negative binomial regression model was used to assess the relationship between vector species-specific SCI and autochthonous dengue cases after accounting for potential confounders in Guangdong, China. The potential interactive effect between the SCI for Ae. albopictus and the SCI for Ae. aegypti on dengue transmission was assessed. The SCI for Ae. aegypti was found to be positively associated with autochthonous dengue transmission (incidence rate ratio: 1.06, 95% confidence interval: 1.03, 1.09). A significant interaction effect between the SCI of Ae. albopictus and the SCI of Ae. aegypti was found, with the SCI of Ae. albopictus significantly reducing the effect of the SCI of Ae. aegypti on autochthonous dengue cases. The difference in SCIs had a positive effect on autochthonous dengue cases. Our results suggest that dengue fever is more transmittable in regions with warmer weather conditions (high SCI for Ae. aegypti). The SCI of Ae. aegypti would be a useful index to predict dengue transmission in Guangdong, China, even in dengue epidemic regions with Ae. albopictus present. The results also support the benefit of the SCI for evaluating dengue outbreak risk in terms of vector sympatry and interactions in the absence of entomology data in future research.