The expression of muscle ankyrin repeat proteins in brown adipose tissue

MARP family members CARP, Ankrd2 and DARP are expressed in the striated muscle, while DARP protein is also detected in brown adipose tissue (BAT). Taking into account recent findings concerning the common origin of muscle and brown fat, expression of CARP and Ankrd2 in mouse BAT was investigated. We...

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Bibliographic Details
Published in:Archives of biological sciences 2011, Vol.63 (4), p.915-920
Main Authors: Rakicevic, Ljiljana, Petrovic, Natasa, Radojkovic, Dragica, Kojic, Snezana
Format: Article
Language:English
Subjects:
ADIPOSE TISSUE
brown adipose tissue
http://www.fao.org/aos/agrovoc#c_129
http://www.fao.org/aos/agrovoc#c_4795
http://www.fao.org/aos/agrovoc#c_5003
http://www.fao.org/aos/agrovoc#c_6259
MARP family
MASCULOS
MICE
MUSCLE
MUSCLES
PROTAINE
PROTEANAS
PROTEINS
RATAN
SOURIS
TEJIDO ADIPOSO
TISSU ADIPEUX
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Summary:MARP family members CARP, Ankrd2 and DARP are expressed in the striated muscle, while DARP protein is also detected in brown adipose tissue (BAT). Taking into account recent findings concerning the common origin of muscle and brown fat, expression of CARP and Ankrd2 in mouse BAT was investigated. We demonstrated Ankrd2 expression in both inactive and thermogenically active BAT, while CARP expression was not detected. Our findings suggest that the expression of Ankrd2 in BAT could be a part of the myogenic transcriptional signature, further supporting the evidence that muscle and brown adipose cells arise from the same myoblastic precursor.
ISSN:0354-4664
1821-4339
DOI:10.2298/ABS1104915R