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Effectiveness of directly observed treatment short course (DOTS) on treatment of tuberculosis patients in public health facilities of Debre Tabor Town, Ethiopia: retrospective study
The objective of this study is to assess effectiveness of directly observed treatment short course (DOTS) in treatment of tuberculosis (TB) patients in all public health facilities of Debre Tabor town, Ethiopia from January 2016 to December 2017. Among 354 TB patients, 53.1% were males. Furthermore...
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| Published in: | BMC research notes 2019-07, Vol.12 (1), p.396-396, Article 396 |
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| cites | cdi_FETCH-LOGICAL-c566t-68b6b85ba7fa9ef15cb2020759fd469350bb89ac47e344120a7ad5c12bda2e8a3 |
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| creator | Genet, Chalachew Melese, Addisu Worede, Abebaw |
| description | The objective of this study is to assess effectiveness of directly observed treatment short course (DOTS) in treatment of tuberculosis (TB) patients in all public health facilities of Debre Tabor town, Ethiopia from January 2016 to December 2017.
Among 354 TB patients, 53.1% were males. Furthermore 22.6%, 40.4%, and 37% were smear positive pulmonary, smear negative pulmonary and extra pulmonary TB respectively. Study also revealed that TB-human immunodeficiency virus (HIV) co-infection and overall TB treatment success rate were 18.1% and 90.7% respectively. Regular weigh follow-up, sputum follow-up and HIV status were significantly associated with treatment success with P-value |
| doi_str_mv | 10.1186/s13104-019-4424-8 |
| format | article |
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Among 354 TB patients, 53.1% were males. Furthermore 22.6%, 40.4%, and 37% were smear positive pulmonary, smear negative pulmonary and extra pulmonary TB respectively. Study also revealed that TB-human immunodeficiency virus (HIV) co-infection and overall TB treatment success rate were 18.1% and 90.7% respectively. Regular weigh follow-up, sputum follow-up and HIV status were significantly associated with treatment success with P-value < 0.001, < 0.001 and 0.334 respectively. But TB treatment success weren't associated with sex (P = 8.62), health facility type (P = 0.749) and TB type (P = 0.778). The study also showed that the overall TB treatment success rate was in line with World Health Organization (WHO) target on treatment success rate. Furthermore the study indicated higher TB-HIV co-infection and variations in conducting regular weight and sputum follow-up among HFs.</description><identifier>ISSN: 1756-0500</identifier><identifier>EISSN: 1756-0500</identifier><identifier>DOI: 10.1186/s13104-019-4424-8</identifier><identifier>PMID: 31300032</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Adolescent ; Adult ; Antitubercular Agents - therapeutic use ; Care and treatment ; Child ; Debre Tabor ; Directly Observed Therapy - methods ; Directly Observed Therapy - statistics & numerical data ; DOTS effectiveness ; Ethiopia - epidemiology ; Female ; Health facilities ; HIV ; HIV Infections - diagnosis ; HIV Infections - epidemiology ; HIV Infections - virology ; Humans ; Male ; Mycobacterium tuberculosis - drug effects ; Outcome Assessment, Health Care - methods ; Outcome Assessment, Health Care - statistics & numerical data ; Patient outcomes ; Public health ; Research Note ; Retrospective Studies ; Sputum - microbiology ; Tuberculosis ; Tuberculosis - drug therapy ; Tuberculosis - epidemiology ; Tuberculosis - microbiology ; World health ; World Health Organization ; Young Adult</subject><ispartof>BMC research notes, 2019-07, Vol.12 (1), p.396-396, Article 396</ispartof><rights>COPYRIGHT 2019 BioMed Central Ltd.</rights><rights>The Author(s) 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c566t-68b6b85ba7fa9ef15cb2020759fd469350bb89ac47e344120a7ad5c12bda2e8a3</citedby><cites>FETCH-LOGICAL-c566t-68b6b85ba7fa9ef15cb2020759fd469350bb89ac47e344120a7ad5c12bda2e8a3</cites><orcidid>0000-0001-8631-5094</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625082/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625082/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31300032$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Genet, Chalachew</creatorcontrib><creatorcontrib>Melese, Addisu</creatorcontrib><creatorcontrib>Worede, Abebaw</creatorcontrib><title>Effectiveness of directly observed treatment short course (DOTS) on treatment of tuberculosis patients in public health facilities of Debre Tabor Town, Ethiopia: retrospective study</title><title>BMC research notes</title><addtitle>BMC Res Notes</addtitle><description>The objective of this study is to assess effectiveness of directly observed treatment short course (DOTS) in treatment of tuberculosis (TB) patients in all public health facilities of Debre Tabor town, Ethiopia from January 2016 to December 2017.
Among 354 TB patients, 53.1% were males. Furthermore 22.6%, 40.4%, and 37% were smear positive pulmonary, smear negative pulmonary and extra pulmonary TB respectively. Study also revealed that TB-human immunodeficiency virus (HIV) co-infection and overall TB treatment success rate were 18.1% and 90.7% respectively. Regular weigh follow-up, sputum follow-up and HIV status were significantly associated with treatment success with P-value < 0.001, < 0.001 and 0.334 respectively. But TB treatment success weren't associated with sex (P = 8.62), health facility type (P = 0.749) and TB type (P = 0.778). The study also showed that the overall TB treatment success rate was in line with World Health Organization (WHO) target on treatment success rate. Furthermore the study indicated higher TB-HIV co-infection and variations in conducting regular weight and sputum follow-up among HFs.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antitubercular Agents - therapeutic use</subject><subject>Care and treatment</subject><subject>Child</subject><subject>Debre Tabor</subject><subject>Directly Observed Therapy - methods</subject><subject>Directly Observed Therapy - statistics & numerical data</subject><subject>DOTS effectiveness</subject><subject>Ethiopia - epidemiology</subject><subject>Female</subject><subject>Health facilities</subject><subject>HIV</subject><subject>HIV Infections - diagnosis</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - virology</subject><subject>Humans</subject><subject>Male</subject><subject>Mycobacterium tuberculosis - drug effects</subject><subject>Outcome Assessment, Health Care - methods</subject><subject>Outcome Assessment, Health Care - statistics & numerical data</subject><subject>Patient outcomes</subject><subject>Public health</subject><subject>Research Note</subject><subject>Retrospective Studies</subject><subject>Sputum - microbiology</subject><subject>Tuberculosis</subject><subject>Tuberculosis - drug therapy</subject><subject>Tuberculosis - epidemiology</subject><subject>Tuberculosis - microbiology</subject><subject>World health</subject><subject>World Health Organization</subject><subject>Young Adult</subject><issn>1756-0500</issn><issn>1756-0500</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNptks1uEzEUhUcIREvhAdggS2xaiSm2Zzw_LJCqNkCkSlkQ2FrXnuvE1WSc2p5AHoz3w2lKlUjIC1vX3zm2r0-WvWX0krGm-hhYwWiZU9bmZcnLvHmWnbJaVDkVlD4_WJ9kr0K4o7RiTcNeZicFKyilBT_N_kyMQR3tBgcMgThDOutTod8SpwL6DXYkeoS4wiGSsHQ-Eu1GH5Cc38zm3y-IGw6ApI-jQq_H3gUbyBqiTfVA7EDWo-qtJkuEPi6JAW17m3YfDr1B5ZHMQTlP5u7X8IFM4tK6tYVPxGP0Lqz3tyQhjt32dfbCQB_wzeN8lv34Mplff8tvZ1-n11e3uRZVFfOqUZVqhILaQIuGCa045bQWrenKqi0EVappQZc1FmXJOIUaOqEZVx1wbKA4y6Z7387BnVx7uwK_lQ6sfCg4v5Dgo9U9SuSqYi0YIaAsTc1UUddKVZ0ySJFqlbw-771SH1bY6dQWD_2R6fHOYJdy4TayqrigDU8G548G3t2PGKJc2aCx72FANwbJuajrBLYsoe_36ALS1exgXHLUO1xeibZgyZLvqMv_UGl0uLLaDWhsqh8JLo4EiYn4Oy5gDEFOZz-PWbZndfq84NE8vZRRuUuv3KdXpvTKXXplkzTvDlv0pPgX1-Iv9Y3uAg</recordid><startdate>20190712</startdate><enddate>20190712</enddate><creator>Genet, Chalachew</creator><creator>Melese, Addisu</creator><creator>Worede, Abebaw</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-8631-5094</orcidid></search><sort><creationdate>20190712</creationdate><title>Effectiveness of directly observed treatment short course (DOTS) on treatment of tuberculosis patients in public health facilities of Debre Tabor Town, Ethiopia: retrospective study</title><author>Genet, Chalachew ; Melese, Addisu ; Worede, Abebaw</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c566t-68b6b85ba7fa9ef15cb2020759fd469350bb89ac47e344120a7ad5c12bda2e8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Antitubercular Agents - therapeutic use</topic><topic>Care and treatment</topic><topic>Child</topic><topic>Debre Tabor</topic><topic>Directly Observed Therapy - methods</topic><topic>Directly Observed Therapy - statistics & numerical data</topic><topic>DOTS effectiveness</topic><topic>Ethiopia - epidemiology</topic><topic>Female</topic><topic>Health facilities</topic><topic>HIV</topic><topic>HIV Infections - diagnosis</topic><topic>HIV Infections - epidemiology</topic><topic>HIV Infections - virology</topic><topic>Humans</topic><topic>Male</topic><topic>Mycobacterium tuberculosis - drug effects</topic><topic>Outcome Assessment, Health Care - methods</topic><topic>Outcome Assessment, Health Care - statistics & numerical data</topic><topic>Patient outcomes</topic><topic>Public health</topic><topic>Research Note</topic><topic>Retrospective Studies</topic><topic>Sputum - microbiology</topic><topic>Tuberculosis</topic><topic>Tuberculosis - drug therapy</topic><topic>Tuberculosis - epidemiology</topic><topic>Tuberculosis - microbiology</topic><topic>World health</topic><topic>World Health Organization</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Genet, Chalachew</creatorcontrib><creatorcontrib>Melese, Addisu</creatorcontrib><creatorcontrib>Worede, Abebaw</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Opposing Viewpoints In Context</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC research notes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Genet, Chalachew</au><au>Melese, Addisu</au><au>Worede, Abebaw</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effectiveness of directly observed treatment short course (DOTS) on treatment of tuberculosis patients in public health facilities of Debre Tabor Town, Ethiopia: retrospective study</atitle><jtitle>BMC research notes</jtitle><addtitle>BMC Res Notes</addtitle><date>2019-07-12</date><risdate>2019</risdate><volume>12</volume><issue>1</issue><spage>396</spage><epage>396</epage><pages>396-396</pages><artnum>396</artnum><issn>1756-0500</issn><eissn>1756-0500</eissn><abstract>The objective of this study is to assess effectiveness of directly observed treatment short course (DOTS) in treatment of tuberculosis (TB) patients in all public health facilities of Debre Tabor town, Ethiopia from January 2016 to December 2017.
Among 354 TB patients, 53.1% were males. Furthermore 22.6%, 40.4%, and 37% were smear positive pulmonary, smear negative pulmonary and extra pulmonary TB respectively. Study also revealed that TB-human immunodeficiency virus (HIV) co-infection and overall TB treatment success rate were 18.1% and 90.7% respectively. Regular weigh follow-up, sputum follow-up and HIV status were significantly associated with treatment success with P-value < 0.001, < 0.001 and 0.334 respectively. But TB treatment success weren't associated with sex (P = 8.62), health facility type (P = 0.749) and TB type (P = 0.778). The study also showed that the overall TB treatment success rate was in line with World Health Organization (WHO) target on treatment success rate. Furthermore the study indicated higher TB-HIV co-infection and variations in conducting regular weight and sputum follow-up among HFs.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>31300032</pmid><doi>10.1186/s13104-019-4424-8</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0001-8631-5094</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Antitubercular Agents - therapeutic use Care and treatment Child Debre Tabor Directly Observed Therapy - methods Directly Observed Therapy - statistics & numerical data DOTS effectiveness Ethiopia - epidemiology Female Health facilities HIV HIV Infections - diagnosis HIV Infections - epidemiology HIV Infections - virology Humans Male Mycobacterium tuberculosis - drug effects Outcome Assessment, Health Care - methods Outcome Assessment, Health Care - statistics & numerical data Patient outcomes Public health Research Note Retrospective Studies Sputum - microbiology Tuberculosis Tuberculosis - drug therapy Tuberculosis - epidemiology Tuberculosis - microbiology World health World Health Organization Young Adult |
| title | Effectiveness of directly observed treatment short course (DOTS) on treatment of tuberculosis patients in public health facilities of Debre Tabor Town, Ethiopia: retrospective study |
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