Increased Red Cell Distribution Width Is Associated With Disease Severity in Hospitalized Adults With SARS-CoV-2 Infection: An Observational Multicentric Study

There is an amenable need for clinically applicable biomarkers in patients with SARS-CoV-2 infection. Red Cell Distribution Width (RDW) has been recently suggested as a prognostic biomarker for COVID-19. This was an observational study enrolling patients between February 26 and May 15 2020. We aimed...

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Published in:Frontiers in medicine 2020-12, Vol.7, p.616292-616292
Main Authors: Karampitsakos, Theodoros, Akinosoglou, Karolina, Papaioannou, Ourania, Panou, Vassiliki, Koromilias, Athanasios, Bakakos, Petros, Loukides, Stelios, Bouros, Demosthenes, Gogos, Charalampos, Tzouvelekis, Argyrios
Format: Article
Language:English
Subjects:
biomarkers
COVID-19
Medicine
mortality
red cell distribution width (RDW)
SARS-CoV-2
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Summary:There is an amenable need for clinically applicable biomarkers in patients with SARS-CoV-2 infection. Red Cell Distribution Width (RDW) has been recently suggested as a prognostic biomarker for COVID-19. This was an observational study enrolling patients between February 26 and May 15 2020. We aimed to validate the association of the previously published RDW threshold of 14.5% with markers of disease progression and mortality. A total number of 193 hospitalized patients with COVID-19 were enrolled and analyzed. Median age was 61 years (95% CI: 58-64). Patients with baseline RDW ≥14.5% ( = 41, 19.2%) presented with more progressive disease compared to patients with baseline RDW
ISSN:2296-858X
2296-858X
DOI:10.3389/fmed.2020.616292