The Diagnosis of Perineural Invasion: A Crucial Factor in Novel Algorithm of Coexistence of Conventional and Nerve-Sparing Radical Hysterectomy

Nerve-sparing radical hysterectomy (NSRH) was introduced to mitigate adverse effects associated with conventional radical hysterectomy (CRH) in cervical cancer. However, the introduction of NSRH was compromised by possible existence of perineural invasion (PNI). Additionally, the coexistence of NSRH...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostics (Basel) 2021-07, Vol.11 (8), p.1308
Main Authors: Skręt, Andrzej, Skręt-Magierło, Joanna Ewa, Książek, Mariusz, Gawlik, Bogusław, Bielatowicz, Joanna, Barnaś, Edyta
Format: Article
Language:English
Subjects:
Biopsy
Cervical cancer
Cervix
Classification
diagnosis
Hysterectomy
Ligaments
Lymphatic system
Mortality
Nervous system
perineural invasion
Risk factors
Tumors
Vagina
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nerve-sparing radical hysterectomy (NSRH) was introduced to mitigate adverse effects associated with conventional radical hysterectomy (CRH) in cervical cancer. However, the introduction of NSRH was compromised by possible existence of perineural invasion (PNI). Additionally, the coexistence of NSRH and CRH is currently the fact. The aim of the study was to review the literature and attempt to construct a novel and preliminary PNI diagnostic algorithm that would establish the coexistence of NSRH and CRH in one system of early-stage cervical cancer (ESCC) surgical treatment. This algorithm takes into account the PNI risk factors and current and future diagnostic methods such as imaging and biopsy.
ISSN:2075-4418
2075-4418
DOI:10.3390/diagnostics11081308